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Malaria

About microscopic forms of life, including Bacteria, Archea, protozoans, algae and fungi. Topics relating to viruses, viroids and prions also belong here.

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Malaria

Postby intali » Fri Oct 26, 2007 3:44 pm

I've been trying to find information about how the structural differences in hemoglobin in individuals affect with sickle cell prevent infection by Plasmodium. But I'm not really finding any information that actually provides a clear correlation between the structural change and the reason for the inability of infection. If someone could give me a pointer in the right direction or has any ideas it would be greatly appreciated. Thanks.
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Postby blcr11 » Fri Nov 02, 2007 6:48 pm

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Postby mcar » Sat Nov 17, 2007 12:49 pm

As the cell sickles, less surface area for oxygen to bind--less nutrients.
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Postby Darby » Sat Nov 24, 2007 2:38 am

Sickled cells are also interpreted as defective / worn out and broken down for recycling, killing the parasites inside.
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