Anticholergenics as possible Nootropics...sorta

[kclo4x]

Alright!
so we know that with caffeine it blocks the adenosine receptors, keeping the adenosine from entering receptor and preventing you to feel tired

if you use caffeine often you get more adenosine receptors and thus the stimulator effects go away, assuming you use the same amount for a long period of time

Anyways my idea is that if you take say 2 or 3 benydril a day, or some other antichollergenic, that eventually it would do basically the same thing as consuming caffeine does

the two acetylcholine receptors would increase in number to compensate, or the actylcholine could just simply increase in quanatiy (or... a little of each?) and then when you stop taking the antichollergenics, all of a sudden there is an excess of what you would naturally have and so it works as a nootropic since from what i know actylcholine has a lot to do with cognition... as well as muscle movement correct?

[mith]

Please tell me you're not going to drug yourself for this experiment.

[kclo4x]

Well actually...


haha jk no i won't i was just wondering if that would work . it seems like it would doesn't it?

[mith]

Think about this scenario, suppose there's a person who has never drank alcohol before. You start him on a diet of beer and wines. Over time he develops a tolerance for alcohol(maybe because of more alcohol dehydrogenase?).

Is this a good thing? Perhaps...but at the same time just because you can drink more doesn't mean you won't feel the same effects of increased alcohol consumption(organ damage, beer belly etc). You also put yourself at the risk of damaging the liver and actually impairing function.

[sdekivit]

that certainly is true, but the fact that the recptor will be up-regulated will occur when blocking the AChR for longer periods. The site of the inhibition will determine the outcome of 'the experiment'.