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GENES PLEASE HELP !!!

Genetics as it applies to evolution, molecular biology, and medical aspects.

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GENES PLEASE HELP !!!

Postby j_todorov » Mon Apr 23, 2007 4:22 pm

Can two parents, who have blue eyes ,to have a child with brown eyes?
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Postby kotoreru » Mon Apr 23, 2007 4:48 pm

No. Not unless there is a mutation or some other phenomenon somewhere along the line.

This is actually quite interesting: males with blue eyes have been shown to have a preference for females with blue eyes. This is thought to be an evolutionary adaptation to avoid fathering offspring that aren't yours.

(Literature tend to simplify it for Mendelian genetics as: BB = brown; bb = blue; Bb = brown).
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Postby j_todorov » Mon Apr 23, 2007 5:50 pm

Thank you very much!!!
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Postby Darby » Wed Apr 25, 2007 2:45 pm

It is possible if a parent has a brown allele but lacks working color processors. That should be a rare occurrence (but I've run into it).
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Postby kotoreru » Wed Apr 25, 2007 3:33 pm

Darby, do you know of any decent links to sites/papers that explain in detail eye colour heredity etc.? I'd love to know more about this.
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Postby Poison » Sat Apr 28, 2007 8:53 pm

yes that's possible. eye color heredity is a bit complex. Multiple modificator genes play role.
That's rara but yes 2 parets with blue eyes CAN have children with brown eyes.
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Postby Poison » Sat Apr 28, 2007 9:08 pm

For more info: (university level)
brown color occurance: front layer of iris has melanin
blue color occurance: front layer lack melanin. Back part has it.
Multiple modificator genes are genes that are not alleles of a trait but playes role on phenotypic expression. They affect pigment production, tones etc. (that's how colors other than blue and brown occurs)
Let's say both of the parents have blue eyes. But one of them (or even both of them) can be Bb but because of multiple modificator genes pigment production can be blocked. So his/her eyes appears to be blue. He/She can give that B to his /her child. So the child now carries the dominant allele B. And the eye color is brown.
Hope this helped.
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Postby MrMistery » Mon Apr 30, 2007 12:34 pm

@ozge
I may be wrong, but from what i remember, if a person has blue eyes he must be recessive for all 3 genes involved. So that would mean it is indeed impossible for the parents with blue eyes to have a brown-eyed child.
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Postby Darby » Mon Apr 30, 2007 5:56 pm

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Postby Poison » Mon Apr 30, 2007 6:05 pm

MrMistery wrote:@ozge
I may be wrong, but from what i remember, if a person has blue eyes he must be recessive for all 3 genes involved. So that would mean it is indeed impossible for the parents with blue eyes to have a brown-eyed child.


Are you sure? I think you are worng. What I wrote is something that is told during our genetic classes. If someone is Bb but melanin production on the front layer is blocked by another gene eyes will appear to be blue. What's more, 2 alleles (brown and blue) and many multiple modificator genes are involved in the heredity of eye color. Some change the tone of the pigment or amount of production. And that's how other colors form.
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