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What is the size of an antibody

Discussion of all aspects of biological molecules, biochemical processes and laboratory procedures in the field.

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Postby blcr11 » Fri Apr 06, 2007 12:37 pm

The crystal structures of antibodies are known. I haven't looked it/them up, but they have to be in the range of 40-50 angstroms in the shortest dimension to something like 150-200 angstroms in the largest--so say a "box of 50 x 50 x 200 angstroms might be a reasonable guess for the "size" of an antibody.

That would be an IgG. IgMs would be larger. A single IgG molecule is much smaller than a bacterium, but the surface of the bacterium gets coated with many such molecules which acts either to agglutinate the bacterium directly, or attract things like macrophages or eosinophils or leukocytes.
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