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how does heat receptors in cells work

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how does heat receptors in cells work

Postby mehdi71000 » Fri Mar 02, 2007 12:32 am

hi how does heat receptors in cells work?
:shock: thanks so much
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Postby dipjyoti » Fri Mar 02, 2007 8:22 am

The Receptors
Few, if any, of the detectors of heat, cold, and pain are specialized transducers (in the way that, for example, the Pacinian corpuscle is). Rather they are transmembrane proteins embedded in the plasma membrane of both sensory neurons and nearby cells (e.g. skin cells). A single neuron may be triggered by several types of these receptors and thus be able to respond to several types of stimuli. Like all sensory spinal neurons, their axons travel to a dorsal root ganglion of the spinal cord, where their cell bodies reside, and then on in to the gray matter of the spinal cord.

Heat
There are several types of heat receptors in the skin. They are all transmembrane proteins in the plasma membrane that open to let in both calcium ions and sodium ions (the latter the source of the action potential). Between them, they cover a range of temperatures.
TRPV4
Warm (~27–34°C)
TRPV3
Warmer (~33–39°C)
TRPV1
Hot (>42°C). Also activated by capsaicin, the active ingredient of hot chili peppers, by camphor, and by acids (protons).
TRPV2
Painfully hot (>52°C)
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Postby Dr.Stein » Fri Mar 02, 2007 12:47 pm

There is a 'machine' that controls the body heat a.k.a. hypothalamus.
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Postby mehdi71000 » Sat Mar 03, 2007 12:20 am

thanks
i ment how does the actual cell detect the energy?
the protain involved. what chemical reactions are involved
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