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Biology Articles » Health and Medicine » Illnesses and Pathobiology » Virology, Pathology, and Clinical Manifestations of West Nile Virus Disease

(Abstract)
- Virology, Pathology, and Clinical Manifestations of West Nile Virus Disease

Virology, Pathology, and Clinical Manifestations of West Nile Virus Disease

Edward B. Hayes,* James J. Sejvar,† Sherif R. Zaki,† Robert S. Lanciotti,* Amy V. Bode,* and Grant L. Campbell*

*Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; and †Centers for Disease Control and Prevention, Atlanta Georgia, USA

(Abstract)

West Nile virus (WNV) causes epidemics of febrile illness, meningitis, encephalitis, and flaccid paralysis. Since it was first detected in New York City in 1999, and through 2004, 16,000 WNV disease cases have been reported in the United States. Over the past 5 years, research on WNV disease has expanded rapidly. This review highlights new information regarding the virology, clinical manifestations, and pathology of WNV disease, which will provide a new platform for further research into diagnosis, treatment, and possible prevention of WNV through vaccination.

Source: Emerging Infectious Diseases,  Vol. 11, No. 8, August 2005


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