To investigate a possible new method based on biophysical principles (scrambler therapy) …

• Abstract
• Introduction
• Materials and Methods
• Results
• Discussion
• Conclusion
• References
• Figures

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Figure 1. Simplified model of scrambler therapy.

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Figure 2. Prototype scrambler therapy ST5.

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Figure 3. VAS trends before and after each treatment session

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Figure 4. Pain intensity difference values (PID: mean±SD VAS score difference before and after each treatment). The gradual flattening of the curve is indicative of a reduction in the differences as the number of treatment sessions increases. The phenomenon is due to a rising pain threshold, which is reflected in a lower pre-treatment baseline VAS, while the post-treatment VAS can never be negative. Several peaks may realistically be ascribed to other possible causes as the disease progresses

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Figure 5. Percentage of patients stratified according to the severity of pain recorded after treatment: no further pain (VAS=0), slight or very slight pain (VAS 1-20), more intense pain (VAS>20).

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Figure 6. Distribution of the patients according to the mean duration of absence of pain after each single application

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