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In this study, the authors present evidence showing that while SERPINI1 is …


Biology Articles » Molecular Biology » Two non-homologous brain diseases-related genes, SERPINI1 and PDCD10, are tightly linked by an asymmetric bidirectional promoter in an evolutionarily conserved manner » References

References
- Two non-homologous brain diseases-related genes, SERPINI1 and PDCD10, are tightly linked by an asymmetric bidirectional promoter in an evolutionarily conserved manner

1.   Rawlings ND, Tolle DP, Barrett AJ: MEROPS: the peptidase database.Nucleic Acids Res 2006, 34:D270-2.       2.   Silverman GA, Bird PI, Carrell RW, Church FC, Coughlin PB, Gettins PG, Irving JA, Lomas DA, Luke CJ, Moyer RW, Pemberton PA, Remold-O'Donnell E, Salvesen GS, Travis J, Whisstock JC: The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature.J Biol Chem 2001, 276:33293-33296.       3.   Irving JA, Pike RN, Lesk AM, Whisstock JC: Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.Genome Res 2000, 10:1845-1864.       4.   Irving JA, Steenbakkers PJ, Lesk AM, Op den Camp HJ, Pike RN, Whisstock JC: Serpins in prokaryotes.Mol Biol Evol 2002, 19:1881-1890.       5.   Potempa J, Korzus E, Travis J: The serpin superfamily of proteinase inhibitors: structure, function, and regulation.J Biol Chem 1994, 269:15957-15960.       6.   Bartuski AJ, Kamachi Y, Schick C, Overhauser J, Silverman GA: Cytoplasmic antiproteinase 2 (PI8) and bomapin (PI10) map to the serpin cluster at 18q21.3.Genomics 1997, 43:321-328.       7.   Rollini P, Fournier RE: A 370-kb cosmid contig of the serpin gene cluster on human chromosome 14q32.1: molecular linkage of the genes encoding alpha 1-antichymotrypsin, protein C inhibitor, kallistatin, alpha 1-antitrypsin, and corticosteroid-binding globulin.Genomics 1997, 46:409-415.       8.   Silverman GA, Bartuski AJ, Cataltepe S, Gornstein ER, Kamachi Y, Schick C, Uemura Y: SCCA1 and SCCA2 are proteinase inhibitors that map to the serpin cluster at 18q21.3.Tumour Biol 1998, 19:480-487.       9.   Sun J, Stephens R, Mirza G, Kanai H, Ragoussis J, Bird PI: A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes.Cytogenet Cell Genet 1998, 82:273-277.       10.   Osterwalder T, Contartese J, Stoeckli ET, Kuhn TB, Sonderegger P: Neuroserpin, an axonally secreted serine protease inhibitor.Embo J 1996, 15:2944-2953.       11.   Ozaki K, Nagata M, Suzuki M, Fujiwara T, Miyoshi Y, Ishikawa O, Ohigashi H, Imaoka S, Takahashi E, Nakamura Y: Isolation and characterization of a novel human pancreas-specific gene, pancpin, that is down-regulated in pancreatic cancer cells.Genes Chromosomes Cancer 1998, 22:179-185.       12.   Chang WS, Chang NT, Lin SC, Wu CW, Wu FY: Tissue-specific cancer-related serpin gene cluster at human chromosome band 3q26.Genes Chromosomes Cancer 2000, 29:240-255.       13.   Yepes M, Lawrence DA: Tissue-type plasminogen activator and neuroserpin: a well-balanced act in the nervous system?Trends Cardiovasc Med 2004, 14:173-180.       14.   Friedman GC, Seeds NW: Tissue plasminogen activator mRNA expression in granule neurons coincides with their migration in the developing cerebellum.J Comp Neurol 1995, 360:658-670.       15.   Parmar PK, Coates LC, Pearson JF, Hill RM, Birch NP: Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells.J Neurochem 2002, 82:1406-1415.       16.   Krueger SR, Ghisu GP, Cinelli P, Gschwend TP, Osterwalder T, Wolfer DP, Sonderegger P: Expression of neuroserpin, an inhibitor of tissue plasminogen activator, in the developing and adult nervous system of the mouse.J Neurosci 1997, 17:8984-8996.       17.   Belorgey D, Sharp LK, Crowther DC, Onda M, Johansson J, Lomas DA: Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB.Eur J Biochem 2004, 271:3360-3367.       18.   Miranda E, Romisch K, Lomas DA: Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum.J Biol Chem 2004, 279:28283-28291.       19.   Benvenga S: Conformational mutations in neuroserpin and familial dementias.Lancet 2002, 360:1696.       20.   Onda M, Belorgey D, Sharp LK, Lomas DA: Latent S49P neuroserpin forms polymers in the dementia familial encephalopathy with neuroserpin inclusion bodies.J Biol Chem 2005, 280:13735-13741.       21.   Davis RL, Shrimpton AE, Holohan PD, Bradshaw C, Feiglin D, Collins GH, Sonderegger P, Kinter J, Becker LM, Lacbawan F, Krasnewich D, Muenke M, Lawrence DA, Yerby MS, Shaw CM, Gooptu B, Elliott PR, Finch JT, Carrell RW, Lomas DA: Familial dementia caused by polymerization of mutant neuroserpin.Nature 1999, 401:376-379.       22.   Davis RL, Shrimpton AE, Carrell RW, Lomas DA, Gerhard L, Baumann B, Lawrence DA, Yepes M, Kim TS, Ghetti B, Piccardo P, Takao M, Lacbawan F, Muenke M, Sifers RN, Bradshaw CB, Kent PF, Collins GH, Larocca D, Holohan PD: Association between conformational mutations in neuroserpin and onset and severity of dementia.Lancet 2002, 359:2242-2247.       23.   Wang YG, Liu HT, Zhang YM, Ma DL: cDNA cloning and expression of an apoptosis-related gene, human TFAR15 gene.Sci China 1999, 42:323-329.       24.   Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, Gotta M, Kanapin A, Le Bot N, Moreno S, Sohrmann M, Welchman DP, Zipperlen P, Ahringer J: Systematic functional analysis of the Caenorhabditis elegans genome using RNAi.Nature 2003, 421:231-237.       25.   Bergametti F, Denier C, Labauge P, Arnoult M, Boetto S, Clanet M, Coubes P, Echenne B, Ibrahim R, Irthum B, Jacquet G, Lonjon M, Moreau JJ, Neau JP, Parker F, Tremoulet M, Tournier-Lasserve E: Mutations within the Programmed Cell Death 10 Gene Cause Cerebral Cavernous Malformations.Am J Hum Genet 2005, 76:42-51.       26.   Trinklein ND, Aldred SF, Hartman SJ, Schroeder DI, Otillar RP, Myers RM: An abundance of bidirectional promoters in the human genome.Genome Res 2004, 14:62-66.       27.   Poschl E, Pollner R, Kuhn K: The genes for the alpha 1(IV) and alpha 2(IV) chains of human basement membrane collagen type IV are arranged head-to-head and separated by a bidirectional promoter of unique structure.Embo J 1988, 7:2687-2695.       28.   Lu K, Lee MH, Hazard S, Brooks-Wilson A, Hidaka H, Kojima H, Ose L, Stalenhoef AF, Mietinnen T, Bjorkhem I, Bruckert E, Pandya A, Brewer HB Jr., Salen G, Dean M, Srivastava A, Patel SB: Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively.Am J Hum Genet 2001, 69:278-290.       29.   Remaley AT, Bark S, Walts AD, Freeman L, Shulenin S, Annilo T, Elgin E, Rhodes HE, Joyce C, Dean M, Santamarina-Fojo S, Brewer HB Jr.: Comparative genome analysis of potential regulatory elements in the ABCG5-ABCG8 gene cluster.Biochem Biophys Res Commun 2002, 295:276-282.       30.   Berger P, Kozlov SV, Cinelli P, Kruger SR, Vogt L, Sonderegger P: Neuronal depolarization enhances the transcription of the neuronal serine protease inhibitor neuroserpin.Mol Cell Neurosci 1999, 14:455-467.       31.   Li Z, Liu Q, Song M, Zheng Y, Nan P, Cao Y, Chen G, Li Y, Zhong Y: Detecting correlation between sequence and expression divergences in a comparative analysis of human serpin genes.Biosystems 2005, 82:226-234.       32.   Scott FL, Eyre HJ, Lioumi M, Ragoussis J, Irving JA, Sutherland GA, Bird PI: Human ovalbumin serpin evolution: phylogenic analysis, gene organization, and identification of new PI8-related genes suggest that two interchromosomal and several intrachromosomal duplications generated the gene clusters at 18q21-q23 and 6p25.Genomics 1999, 62:490-499.       33.   Schneider SS, Schick C, Fish KE, Miller E, Pena JC, Treter SD, Hui SM, Silverman GA: A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.Proc Natl Acad Sci U S A 1995, 92:3147-3151.       34.   Zhang LF, Ding JH, Yang BZ, He GC, Roe C: Characterization of the bidirectional promoter region between the human genes encoding VLCAD and PSD-95.Genomics 2003, 82:660-668.       35.   West AB, Lockhart PJ, O'Farell C, Farrer MJ: Identification of a novel gene linked to parkin via a bi-directional promoter.J Mol Biol 2003, 326:11-19.       36.   West A, Farrer M, Petrucelli L, Cookson M, Lockhart P, Hardy J: Identification and characterization of the human parkin gene promoter.J Neurochem 2001, 78:1146-1152.       37.   Schlossmacher MG, Frosch MP, Gai WP, Medina M, Sharma N, Forno L, Ochiishi T, Shimura H, Sharon R, Hattori N, Langston JW, Mizuno Y, Hyman BT, Selkoe DJ, Kosik KS: Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies.Am J Pathol 2002, 160:1655-1667.       38.   Sumiyama K, Ruddle FH: Regulation of Dlx3 gene expression in visceral arches by evolutionarily conserved enhancer elements.Proc Natl Acad Sci U S A 2003, 100:4030-4034.       39.   Marty T, Vigano MA, Ribeiro C, Nussbaumer U, Grieder NC, Affolter M: A HOX complex, a repressor element and a 50 bp sequence confer regional specificity to a DPP-responsive enhancer.Development 2001, 128:2833-2845.       40.   Weber JR, Skene JH: Identification of a novel repressive element that contributes to neuron-specific gene expression.J Neurosci 1997, 17:7583-7593.       41.   Swamynathan SK, Piatigorsky J: Orientation-dependent influence of an intergenic enhancer on the promoter activity of the divergently transcribed mouse Shsp/alpha B-crystallin and Mkbp/HspB2 genes.J Biol Chem 2002, 277:49700-49706.    


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