Table 04 - Biology Online

Table 4

Subset of E. histolytica genes upregulated by exposure to Trichostatin A.

Probe ID

GenBank ID

Description

Fold-change

FDR

489.m00024_at

XM_643195

hypothetical protein

39.96

7.60E-16

14.m00310_at

XM_651236

hypothetical protein

39.67

2.32E-20

295.m00030_at

XM_644416

conserved hypothetical protein

38.77

2.29E-20

522.m00017_at

XM_643097

hypothetical protein

20.45

4.53E-15

418.m00028_at

XM_643537

70 kDa heat shock protein, putative

17.45

6.71E-10

36.m00204_s_at

XM_650008

hypothetical protein

14.84

1.22E-08

451.m00037_s_at

XM_643383

hypothetical protein

14.68

3.96E-04

556.m00022_x_at

XM_643031

hypothetical protein

14.37

5.75E-07

12.m00306_at

XM_651386

hypothetical protein

13.25

1.64E-05

376.m00054_s_at

XM_643784

hypothetical protein

13.02

1.62E-10

564.m00020_x_at

XM_643013

hypothetical protein

12.93

8.19E-10

82.m00164_s_at

XM_648353

hypothetical protein

12.88

8.00E-12

28.m00298_s_at

XM_650406

hypothetical protein

11.79

5.97E-09

110.m00118_at

XM_647568

Rho family GTPase

11.60

2.26E-14

50.m00195_s_at

XM_649449

hypothetical protein

11.36

3.02E-05

135.m00094_at

XM_646923

hypothetical protein

10.98

2.38E-08

493.m00030_x_at

XM_643175

hypothetical protein

10.25

1.40E-24

337.m00049_at

XM_644075

hypothetical protein

9.93

5.43E-07

164.m00105_x_at

XM_646368

hypothetical protein

9.92

4.32E-05

847.m00011_x_at

XM_642805

hypothetical protein

9.63

9.76E-05

205.m00100_s_at

XM_645582

hypothetical protein

9.48

3.01E-08

373.m00052_at

XM_643804

hypothetical protein

8.71

1.14E-06

395.m00030_x_at

XM_643673

protein kinase, putative

8.68

6.64E-04

749.m00013_s_at

XM_642848

hypothetical protein

8.61

1.85E-03

227.m00077_at

XM_645230

hypothetical protein

8.40

1.70E-08

728.m00012_x_at

XM_642855

hypothetical protein

8.37

5.83E-06

460.m00025_x_at

XM_643328

hypothetical protein

8.00

3.05E-02

167.m00116_x_at

XM_646306

hypothetical protein

7.98

3.77E-03

621.m00019_at

XM_642928

hypothetical protein

7.84

8.57E-06

584.m00019_at

XM_642979

heat shock protein 70, putative

7.82

5.54E-06

477.m00021_at

XM_643239

hypothetical protein

7.60

1.27E-03

123.m00123_x_at

XM_647209

conserved hypothetical protein

7.48

3.84E-05

76.m00146_at

XM_648554

hypothetical protein

7.34

1.75E-04

89.m00125_s_at

XM_648139

hypothetical protein

7.32

2.51E-05

220.m00068_x_at

XM_645332

hypothetical protein

7.14

2.48E-03

263.m00053_at

XM_644795

hypothetical protein

6.95

2.56E-04

804.m00006_x_at

XM_642821

hypothetical protein

6.94

2.44E-04

72.m00179_at

XM_648717

hypothetical protein

6.85

1.17E-04

211.m00072_at

XM_645468

zinc finger protein, putative

6.80

5.04E-03

102.m00082_at

XM_647784

hypothetical protein

6.74

6.19E-03

411.m00025_x_at

XM_643570

hypothetical protein

6.68

8.26E-03

162.m00085_at

XM_646412

predicted protein

6.61

3.81E-06

157.m00087_x_at

XM_646502

conserved hypothetical protein

6.50

8.44E-04

12.m00326_at

XM_651342

hypothetical protein

6.42

4.10E-04

52.m00169_x_at

XM_649399

hypothetical protein

6.39

2.21E-03

22.m00288_at

XM_650731

hypothetical protein

6.28

6.49E-04

71.m00129_at

XM_648728

hypothetical protein

6.16

5.70E-05

6.m00428_at

XM_651814

hypothetical protein

6.10

1.46E-04

496.m00027_x_at

XM_643167

hypothetical protein

5.98

9.24E-06

135.m00113_at

XM_646942

hypothetical protein

5.91

4.26E-03

The mean trophozoite expression value for E. histolytica 200:NIH strain under standard culture conditions, the fold-change in TSA treated parasites, FDR, GenBank ID number, and gene annotations are shown. Genes in bold have been confirmed by RT-PCR. Genes regulated during trophozoite to cyst development are shown in italics. Additional loci represented by crosshybridizing _s_at probe sets are as follows: 36.m00204_s_at: 88.m00180; 451.m00037_s_at: 467.m00031 and 50.m00196; 376.m00054_s_at: 116.m00123; 82.m00164_s_at: 82.m00157; 28.m00298_s_at: 481.m00033 and 90.m00158; 205.m00100_s_at: 105.m00129; 749.m00013_s_at: 142.m00151; 89.m00125_s_at: 357.m00038.

Ehrenkaufer et al. BMC Genomics 2007 8:216 doi:10.1186/1471-2164-8-216

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Table 04
- Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica

Table 4

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Table 04 - Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica

Table 4

Table 04
- Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica