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This work represents the first genome-wide analysis of histone acetylation and its …

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Table 03
- Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica

Table 3

E. histolytica genes regulated by exposure short-chain fatty acids.
Probe ID	GenBank ID	Description	Fold-change	FDR

Up-regulated
122.m00139_at	XM_647238	ADP-ribosylation factor, putative	2.11	1.97E-02
14.m00310_at	XM_651236	hypothetical protein	6.70	2.09E-03
205.m00100_s_at	XM_645582	hypothetical protein	2.57	2.86E-02
22.m00285_at	XM_650728	hypothetical protein	19.36	1.19E-11
295.m00030_at	XM_644416	conserved hypothetical protein	20.75	3.12E-14
418.m00028_at	XM_643537	70 kDa heat shock protein, putative	6.03	1.97E-02
522.m00017_at	XM_643097	hypothetical protein	3.41	6.42E-03
522.m00018_x_at	XM_643100	hypothetical protein	2.78	1.19E-03
585.m00015_s_at	XM_642978	conserved hypothetical protein	3.16	1.82E-03
72.m00179_at	XM_648717	hypothetical protein	6.25	5.69E-04
Down-regulated
5.m00482_at	XM_651923	protein kinase, putative	-2.82	2.86E-02

The mean trophozoite expression value for E. histolytica 200:NIH strain under standard culture conditions, the fold-change in SCFA treated parasites, FDR, GenBank ID number, and gene annotations are shown. Ten genes are upregulated and one is downregulated. 205.m00100_s_at also represents 105.m00129.
Ehrenkaufer et al. BMC Genomics 2007 8:216 doi:10.1186/1471-2164-8-216

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