We are grateful to Henry Huang (Washington University), John Wootton (National Center for Biotechnology Information, Bethesda, MD), Steve Beverley (Washington University), Rubens Belfort, Jr. (Paulista School of Medicine, Sâo Paulo, Brazil), Jack Remington (Palo Alto Medical Research Foundation, Palo Alto, CA), Jack Frenkel (Sante Fe, NM), and Ricardo Vitor (Fed. Univ. Minas Gerais, Belo Horizonte, Brazil) for strains of T. gondii and to Robert Cole (Washington University) and Julie Nawas (Washington University) for expert technical assistance. This work was supported by National Institutes of Health Grants AI036629 and AI059176 (to L.D.S.), the Biotechnology and Biological Sciences Research Council, the Wellcome Trust (J.W.A.), U.S. Department of Agriculture CRIS Project 1265-42000-010 (to B.M.R.), and the Department of Microbiology, University of Tennessee (C.S.).
Footnotes
Abbreviations: E, Europe; LD, linkage disequilibrium; MRCA, most recent common ancestry; NA, North America; SA, South America.

To whom correspondence may be addressed. E-mail: benjamin.rosenthal@ars.usda.gov
or sibley@wustl.edu
Freely available online through the PNAS open access option.
Author contributions: A.K., B.F., C.S., and L.D.S. designed research; A.K., B.F., and C.S. performed research; A.K., C.S., J.P.D., M.L.D., J.W.A., and B.M.R. contributed new reagents/analytic tools; A.K., J.W.A., B.M.R., and L.D.S. analyzed data; and B.M.R. and L.D.S. wrote the paper.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
This article contains supporting information online at www.pnas.org/cgi/content/full/0702356104/DC1.
© 2007 by The National Academy of Sciences of the USA