Toward an “electronic nose” to sniff out kidney disease in exhaled breath
in Israel have identified the key substances in exhaled breath
associated with healthy and diseased kidneys — raising expectations,
they say, for development of long-sought diagnostic and screening tests
that literally sniff out chronic renal failure (CRF) in its earliest
and most treatable stages. Their report is in the current issue of ACS Nano, a monthly journal.
The scientists describe tests of an experimental “electronic nose” on exhaled breath of laboratory rats with no kidney function and normal kidney function. The device identified 27 so-called volatile organic compounds that appear only in the breath of rats with CRF. The results presented in this study raise expectations for future capabilities for diagnosis, detection, and screening various stages of kidney disease,” they said, noting that the tests could detect patients with early disease who could be treated in ways that could slow its progression.
-- News release courtesy of American Chemical Society
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