The authors studied tissue engineering in space by using cartilage as a …

• Abstract
• Introduction
• Materials and Methods
• Results and Discussion
• Footnotes
• References
• Figures
• Table

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Figure 1. Experimental design. Cartilage cells were seeded onto polymer scaffolds, and the resulting constructs were cultivated in rotating bioreactors first for 3 months on Earth and then for 4 additional months either on the Mir Space Station (10⁴-10⁶ g) or on Earth (1 g). 

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Figure 2. Cell viability postflight. Cells isolated from a 7-month construct from the Mir group after 2 days of monolayer culture. (×200.) Intracellular esterase activity is indicated by green color. 

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Figure 3. Construct structure. (A and B) Full cross sections of constructs from Mir and Earth groups. (×10.) (C and D) Representative areas at the construct surfaces. (×200.) GAG is stained red with safranin-O. 

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Figure 4. Construct ultrastructure. Transmission electron micrographs of constructs from Mir (A) and Earth (B) groups at magnifications of ×3,500 and ×120,000 (Inset).

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