This is the first demonstration of an enzyme activity transferring a nucleotidyl …

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Biology Articles » Biochemistry » Enzymology » Thiamine diphosphate adenylyl transferase from E. coli: functional characterization of the enzyme synthesizing adenosine thiamine triphosphate » Conclusion

Conclusion

- Thiamine diphosphate adenylyl transferase from E. coli: functional characterization of the enzyme synthesizing adenosine thiamine triphosphate

The discovery of a new thiamine compound, AThTP [4], as well as of its synthesizing enzyme in the present study, along with the recent findings concerning ThTP [1,3,11] and the discovery of riboswitches [12,13] underline the great diversity of thiamine biochemistry and is strongly in favor of one or several non-cofactor roles of thiamine derivatives in living organisms.