table of contents 
Since only studies on human enzyme are likely to be of value …
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Frey PA: The Leloir pathway: a mechanistic imperative for three enzymes to change the stereochemical configuration of a single carbon in galactose. FASEB J 1996, 10:461-470. |
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Novelli G, Reichardt JK: Molecular basis of disorders of human galactose metabolism: past, present, and future. Mol Genet Metab 2000, 71:62-65. |
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Petry KG, Reichardt JK: The fundamental importance of human galactose metabolism: lessons from genetics and biochemistry. Trends Genet 1998, 14:98-102. |
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Stambolian D, Ai Y, Sidjanin D, Nesburn K, Sathe G, Rosenberg M, Bergsma DJ: Cloning of the galactokinase cDNA and identification of mutations in two families with cataracts. Nat Genet 1995, 10:307-312. |
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Verhees CH, Koot DG, Ettema TJ, Dijkema C, de Vos WM, van der Oost J: Biochemical adaptations of two sugar kinases from the hyperthermophilic archaeon Pyrococcus furiosus. Biochem J 2002, 366:121-127. |
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Schell MA, Wilson DB: Purification and properties of galactokinase from Saccharomyces cerevisiase. J Biol Chem 1977, 252:1162-1166. |
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Timson DJ, Reece RJ: Kinetic analysis of yeast galactokinase: Implications for transcriptional activation of the GAL genes. Biochimie 2002, 84:265-272. |
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Foglietti MJ, Percheron F: Purification et mécanisme d'action d'une galactokinase végétale. Biochimie 1976, 58:499-504. |
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| 9. |
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Dey PM: Galactokinase of Vicia faba seeds. Eur J Biochem 1983, 136:155-159. |
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| 10. |
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Ballard FJ: Kinetic studies with liver galactokinase. Biochem J 1966, 101:70-75. |
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| 11. |
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Walker DG, Khan HH: Some properties of galactokinase in developing rat liver. Biochem J 1968, 108:169-175. |
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| 12. |
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Timson DJ, Reece RJ: Functional analysis of disease-causing mutations in human galactokinase. Eur J Biochem 2003, 270:1767-1774. |
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Platt A, Ross HC, Hankin S, Reece RJ: The insertion of two amino acids into a transcriptional inducer converts it into a galactokinase. Proc Natl Acad Sci USA 2000, 97:3154-3159. |
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| 14. |
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Thoden JB, Holden HM: Molecular structure of galactokinase. J Biol Chem 2003, 278:33305-33311. |
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| 15. |
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Tsakiris S, Marinou K, Schulpis KH: The in vitro effects of galactose and its derivatives on rat brain Mg2+-ATPase activity. Pharmacol Toxicol 2002, 91:254-257. |
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Bosch AM, Bakker HD, van Gennip AH, van Kempen JV, Wanders RJ, Wijburg FA: Clinical features of galactokinase deficiency: a review of the literature. J Inherit Metab Dis 2002, 25:629-634. |
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Yang J, Fu X, Jia Q, Shen J, Biggins JB, Jiang J, Zhao J, Schmidt JJ, Wang PG, Thorson JS: Studies on the substrate specificity of Escherichia coli galactokinase. Org Lett 2003, 5:2223-2226. |
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| 18. |
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Gulbinsky JS, Cleland WW: Kinetic studies of Escherichia coli galactokinase. Biochemistry 1968, 7:566-575. |
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| 19. |
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Sherson S, Gy I, Medd J, Schmidt R, Dean C, Kreis M, Lecharny A, Cobbett C: The arabinose kinase, ARA1, gene of Arabidopsis is a novel member of the galactose kinase gene family. Plant Mol Biol 1999, 39:1003-1012. |
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| 20. |
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Fersht A: Structure and mechanism in protein science: a guide to enzyme catalysis and protein folding. New York: WH Freeman 1999.  |
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Fersht AR, Shi JP, Knill-Jones J, Lowe DM, Wilkinson AJ, Blow DM, Brick P, Carter P, Waye MM, Winter G: Hydrogen bonding and biological specificity analysed by protein engineering. Nature 1985, 314:235-238. |
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Fersht AR: Relationships between apparent binding energies measured in site-directed mutagenesis experiments and energetics of binding and catalysis. Biochemistry 1988, 27:1577-1580. |
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Wang W, Malcolm BA: Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange site-directed mutagenesis. Biotechniques 1999, 26:680-682. |
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Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254. |
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| 25. |
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Marquardt D: An algorithm for least squares estimation of nonlinear parameters. SIAM J Appl Math 1963, 11:431-441.  |
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| 26. |
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Cornish-Bowden A: Fundamentals of enzyme kinetics. London, UK: Portland Press 1995.  |
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