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Large-scale expressed sequence tag (EST) – based bioinformatics analysis deal with the heterogenous …


Biology Articles » Bioinformatics » In silico identification and comparative analysis of differentially expressed genes in human and mouse tissues » Figures

Figures
- In silico identification and comparative analysis of differentially expressed genes in human and mouse tissues

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Figure 1: Number of genes identified as differentially expressed using different p value thresholds in 94 human and 99 mouse normal tissues

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Figure 2 : Comparison of human genes identified as differentially expressed by EST analysis with the microarray data for 17 tissues

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Figure 3: Tissue expression profiles of strongly positively correlated orthologs 

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 Figure 4: Tissue expression profiles of human KIAA0748 and its designated mouse ortholog, 5830405N20Rik 

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Figure 5: Tissue expression profiles of strongly negatively correlated orthologs

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Figure 6: Library classification procedure. A triplet of fields consisting of tissue, organ, and title for each EST library from the dbEST report files was extracted. For triplets with records containing the same description under both tissue and organ or no record for one, but not both, the library can be automatically classified into the category described in the tissue/organ field. This automatic assignment was then checked with title to avoid omission of useful information, such as disease state, that could be hidden in the title fields. In some cases (case 2 and 4), the tissue and organ fields were different or both were empty. If different, the library was temporarily classified according to tissue, then modified manually if the other two fields contained more information that could be used for the modification. If both were null, the classification relied on the title.

 

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