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To determine whether estradiol-to-progesterone (E2/P) ratios at the time of embryo …


Biology Articles » Reproductive Biology » Serum estradiol/progesterone ratio on day of embryo transfer may predict reproductive outcome following controlled ovarian hyperstimulation and in vitro fertilization » Tables

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- Serum estradiol/progesterone ratio on day of embryo transfer may predict reproductive outcome following controlled ovarian hyperstimulation and in vitro fertilization

Table 1

Comparison between different parameters for clinical pregnancies, preclinical abortions and non-conception cycles.


Clinical pregnancies
Preclinical abortions
Not pregnant
P valuea

(n = 49)
(n = 27)
(n = 163)

Age (y)
32.2 ± 3.6
30.8 ± 3.3
33.1 ± 4.0
Basal FSH (IU/L)
7.0 ± 2.6
7.2 ± 3.1
7.5 ± 2.5
NS
Peak estradiol (pg/mL)
1325 ± 816
1110 ± 586
1143 ± 864
NS
Peak progesterone (ng/mL)
8.5 ± 5
10.1 ± 6.2
8.2 ± 6.0
NS
No. oocytes/patient
10.7 ± 6.4
10.7 ± 5.7
7.9 ± 5.8
Duration of stimulation
9.8 ± 1.3
9.8 ± 1.1
10.3 ± 1.4
NS
No. oocytes/fertilized
7.3 ± 4.3
6.9 ± 4.3
4.7 ± 3.6
No. embryo transfer
2.8 ± 0.4
2.7 ± 0.4
2.4 ± 0.9
NS
rFSH dosage (ampoules)
26.6 ± 6.8
31.4 ± 8.0
30.8 ± 10.4
NS

Note: Values are means ± SD. NS = not significant.

a For the three groups (Kruskal-Wallis test).

Gruber et al. Journal of Experimental & Clinical Assisted Reproduction 2007 4:1   doi:10.1186/1743-1050-4-1

Table 2

Luteal phase characteristics of E2, P and the E2/P ratio of clinical pregnancies, preclinical abortions and non-pregnant cycles.


Clinical pregnancies
Preclinical abortions
Not pregnant
P valuea
E2 on OI +4 days(pg/mL)
925.4 ± 634.8
792.0 ± 586.4
812.1 ± 794.5
NS
P on OI +4 days (ng/mL)
54.0 ± 24.9
68.6 ± 60.5
56.7 ± 34.4
NS
E2/P Ratio on OI +4 days
18.2 ± 11.5
10.3 ± 8.5
11.8 ± 10.0
0.010





E2 on OI +5 days (pg/mL)
1612.5 ± 1118.9
1210.4 ± 576.6
1257.4 ± 905.2
NS
P on OI +5 days (ng/mL)
101.4 ± 52.6
131.5 ± 66.6
110.6 ± 56.3
NS
E2/P Ratio on OI +5 days
18.1 ± 11.3
9.3 ± 6.3
8.7 ± 7.9
0.005





E2 on OI +7 days (pg/mL)
2416 ± 787.9
2456.5 ± 854.9
2032.0 ± 837.4
NS
P on OI +7 days (ng/mL)
170.9 ± 57.2
187.0 ± 28.2
198.5 ± 118.4
NS
E2/P Ratio on OI +7 days
15.4 ± 6.2
6.5 ± 7.6
5.8 ± 10.7

Note: Values are means ± SD. NS = not significant. OI = ovulation induction.

a = For the three groups (Kruskal-Wallis test).

Gruber et al. Journal of Experimental & Clinical Assisted Reproduction 2007 4:1   doi:10.1186/1743-1050-4-1

 


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