To determine whether estradiol-to-progesterone (E2/P) ratios at the time of embryo …

• Abstract
• Background
• Patients and methods
• Results
• Discussion
• Conclusion
• References
• Figure
• Tables

Biology Articles » Reproductive Biology » Serum estradiol/progesterone ratio on day of embryo transfer may predict reproductive outcome following controlled ovarian hyperstimulation and in vitro fertilization » Conclusion

Conclusion

- Serum estradiol/progesterone ratio on day of embryo transfer may predict reproductive outcome following controlled ovarian hyperstimulation and in vitro fertilization

We conclude that moderately increased P values in the early luteal phase was associated with higher E₂/P ratios and better pregnancy outcomes, whereas a high increase in P values in combination with a decrease in E₂values (reflected by a low E₂/P ratio) append to indicate poor reproductive outcome. Consequently, this retrospective study implies that in the latter setting the embryo will encounter a poorly receptive endometrium on the day of transfer, resulting in impaired implantation.

To our knowledge, this is the first study specifically evaluating E₂/P ratio in relation to IVF outcome. Further study is needed to examine whether the E₂/P ratios could be used as a prognostic test to predict which women will have a clinical pregnancy in the setting of advanced reproductive technologies following a COH.