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The reproductive, developmental, and postnatal toxicity of 14 select chemicals and mixtures that …


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Biology Articles » Toxicology » Reproductive and Developmental Toxicity of the Components of Gasoline

Abstract
- Reproductive and Developmental Toxicity of the Components of Gasoline

Reproductive and Developmental Toxicity of the Components of Gasoline

by Richard G. Skalko

The reproductive, developmental, and postnatal toxicity of 14 select chemicals and mixtures that are components of gasoline has been reviewed. The majority of experimental analyses have been performed as either variations of the accepted segment 2 protocol or as traditional teratology studies. Specific deficiencies in the present database have been identified and are most obvious in the evaluation of reproductive and postnatal effects. It is recommended that future studies address the continuing need for assessment in multiple species and over a range of dosages with specific emphasis on the impact of route of administration on the results obtained.

Envirornmental Health Perspectives Supplements 101 (Sutppl. 6):143-149 (1993).


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