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The discovery that peptide nucleic acids (PNA) mimic DNA and RNA by …


Biology Articles » Biochemistry » Nucleic Acid Biochemistry » Peptide nucleic acid–DNA duplexes: Long range hole migration from an internally linked anthraquinone » Miscellaneous

Miscellaneous
- Peptide nucleic acid–DNA duplexes: Long range hole migration from an internally linked anthraquinone

Acknowledgments

We thank Professor Loren Williams of Georgia Tech for many helpful discussions and Professor W. David Wilson and Dr. Daoyuan Ding of Georgia State University for preparation of the PNA(AQ)/DNA hybrid computer model. Densitometry was performed in the Wilson lab with the assistance of Katherine Hopkins. This work was supported by funding from the National Institutes of Health and the National Science Foundation, for which we are grateful.


Footnotes

  •   To whom reprint requests should be addressed.

  • ABBREVIATIONS:
    PNA,
    peptide nucleic acid;
    AQ,
    anthraquinone derivative;
    8-OxoG,
    7,8-dihydro-8-oxoguanine
  • Copyright © 1997, The National Academy of Sciences of the USA


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