Login

Join for Free!
111306 members
table of contents table of contents

Findings in this study indicate that the peroxisome does not have an …


Biology Articles » Cell biology » Origin and evolution of the peroxisomal proteome » Table

Table
- Origin and evolution of the peroxisomal proteome

..................................................

Table 1 Proteins localized in the peroxisome in S. cerevisiae and R. norvegicus. Gene names are from SGD, Swissprot or GeneBank. Proteins in the same row are orthologous to each other, whenever there is a "one to many" orthology relationship this is indicated by boxes containing several rows. Absence of the gene or absence of evidence of a peroxisomal localization of the encoded protein is indicated by a dash. Proteins that show homology with components of the ERAD pathways are indicated with names in bold and a comment indicating that homology. For each orthologous group, the annotated function and the phylogenetic origin is indicated (euk: eukaryotic no bacterial homologs; euk (a.o.): presence of bacterial homologs but the phylogenetic reconsructions indicates an ancient origin derived from the common ancestor of eukaryotes and archaea; alpha: alpha-proteobacterial origin; actinomyc.: derived from the actinomycetales; cyanobac.: cyanobacterial origin; u, unresolved phylogenetic origin.
S. cerevisiae
R. norvegicus
Origin
Function (comment)
PEX1
PEX1
euk (a.o)
Peroxisome organization and biogenesis (Homologous to ERAD protein Cdc48)
PEX2
PEX2
euk
Peroxisome organization and biogenesis (Homologous to ERAD protein Hrd1)
PEX3
PEX3
euk
Peroxisome organization and biogenesis
PEX4
PEX4
Euk
Peroxisome organization and biogenesis (Homologous to ERAD protein Ubc1)
PEX5
PEX5
euk (a.o)
Peroxisome organization and biogenesis (Homologous to ERAD protein Hrd3)
PEX6
PEX6
euk (a.o)
Peroxisome organization and biogenesis
PEX7
PEX7
Euk
Peroxisome organization and biogenesis
PEX8
-
Euk
Peroxisome organization and biogenesis
PEX10
PEX10
Euk
Peroxisome organization and biogenesis (Homologous to ERAD protein Hrd1)
-
PEX11
euk (a.o)
Peroxisome organization and biogenesis
PEX12
PEX12
euk
Peroxisome organization and biogenesis
PEX13
PEX13
euk
Peroxisome organization and biogenesis
PEX14
PEX14
euk (a.o)
Peroxisome organization and biogenesis
PEX15
-
euk
Peroxisome organization and biogenesis
-
PEX16
euk
Peroxisome organization and biogenesis
PEX17
-
euk
Peroxisome organization and biogenesis
PEX18
-
euk
Peroxisome organization and biogenesis
PEX19
PEX19
euk
Peroxisome organization and biogenesis
PEX21
-
euk
Peroxisome organization and biogenesis
PEX22
-
euk
Peroxisome organization and biogenesis
PEX25
-
euk
Peroxisome organization and biogenesis
-
PEX26
euk
Peroxisome organization and biogenesis
PEX27
-
euk
Peroxisome organization and biogenesis
PEX28
-
euk
Peroxisome organization and biogenesis
PEX29
-
euk
Peroxisome organization and biogenesis
PEX30
-
euk
Peroxisome organization and biogenesis
PEX31
-
euk
Peroxisome organization and biogenesis
PEX32
-
euk
Peroxisome organization and biogenesis
ANT1
PMP34
euk
Adenine nucleotide transporter
-
PMP24
euk
Peroxisomal membrane protein
-
PMP22
euk
Peroxisomal membrane protein
-
PAHX
U
Phytanoyl-CoA dioxygenase
-
gi-6912418
U
2-hydroxyphytanoyl-CoA lyase
-
PTE2B
alpha
peroxisomal long chain acyl-CoA thioesterase Ib
TES1
PTE1_MOUSE
alpha
Peroxisomal acyl-coenzyme A thioester hydrolase 1
CTA1
CATALASE
euk (a.o)
Catalase A
FOX1
OXRTA2
U
acyl-CoA oxidase
gi-1684747
U


CAO3_RAT
U


FOX2
gi-13242303
alpha
peroxisomal multifunctional beta-oxidation protein
gi-4105269
alpha
putative peroxisomal 2,4-dienoyl-CoA reductase

gi-5052204
alpha
putative short-chain dehydrogenase/reductase

FOX3
gi-6978429
U
peroxisomal 3-oxoacyl CoA thiolase
-
ECHP_RAT
U
Peroxisomal bifunctional enzyme
-
SCP2
U
sterol carrier protein-2
IDP3
gi-13928690
U
Peroxisomal NADP-dependent isocitrate dehydrogenase
ECI1
gi-6755026
alpha
enoyl-CoA isomerase
DCI1
alpha


-
BAAT
alpha
bile acid-Coenzyme A: amino acid N-acyltransferase
-
gi-12002203
actinomyc.
alkyl-dihydroxyacetonephosphate synthase
-
DAPT_RAT
actinomyc.
Dihydroxyacetone phosphate acyltransferase
-
AGT
cyanobac.
alanine-glyoxylate aminotransferase
-
gi-6679507
U
pipecolic acid oxidase
-
URIC_RAT
U
Urate oxidase
PXA1
PMP70
U
fatty acid transport
ALDP
U
ATP-binding cassette

ALDPR
U
ATP-binding cassette

FAA1
-
euk

FAA2
LCF2
U
Long-chain-fatty-acid--CoA ligase
LACS
U


FAT1
VLACS
U
Fatty acid transport
-
gi-14091775
U
Hydroxyacid oxidase 3 (medium-chain)
-
gi-6754156
U
Hydroxyacid oxidase 1
-
GTK1_RAT
U
Glutathyhion-S transferase
-
AMCR
U
2-arylpropionyl-CoA epimerase
-
FIS1
euk
Peroxisome fission
FAT2
-
alpha
probable AMP-binding protein
CIT2
-
U
Citrate synthase
GPD1
-
alpha
glycerol-3-phosphate dehydrogenase
MDH3
-
U
malate dehydrogenase
LYS1
-
euk
Lysine biosynthesis, saccharopine dehydrogenase
LYS4
-
U
Lysine biosynthesis
PNC1
-
U
NAD(+) salvage pathway
NPY1
-
alpha
NADH diphosphatase (pyrophosphatase)
STR3
-
U
Sulfur Transfer
YGR154C
-
U

MLS1
-
U
Malate synthase 1
MLS2
-
U
Malate synthase 2
EMP24
-
euk
Vesicle organization and biogenesis
ERG1
-
U
Ergosterol biosynthesis
ERG6
-
U
Ergosterol biosynthesis
RHO1
-
euk
GTP-binding protein
SPS19
-
U
2,4-dienoyl-CoA reductase
YOR084W
-
euk
Peroxisome organization and biogenesis
YMR204C
-
euk

CAT2
-
euk
Carnitine acetyltransferase
PCD1
-
alpha
Nudix hydrolase
AAT2
-
euk
Aspartate aminotransferase
PXA2
-
U
Peroxisomal ATP-binding cassette, fatty acid transport
VPS1
-
euk
Dynamin 1

..................................................

Source: Biology Direct 2006, 1:8.


rating: 0.00 from 0 votes | updated on: 13 Feb 2007 | views: 4988 |

Rate article:







excellent!bad…