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Tables
- Multiple links between transcription and splicing

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TABLE 1. Candidate proteins linking transcription and pre-mRNA splicing

Protein Link to transcription Link to splicing Reference
Mammalian cells
   SCAFs Bind CTD SR-like proteins Yuryev et al. 1996
   WT-1 Transcription factor Binds U2AF65 Davies et al. 1998
   PGC-1 Coactivator Regulates alternative splicing Monsalve et al. 2000
   CA150 Elongation factor Binds SF1 Goldstrohm et al. 2001
Present in spliceosome Zhou et al. 2002
   XAB2 Transcription factor Present in spliceosome Zhou et al. 2002
   SKIP Transcription factor Present in spliceosome Zhou et al. 2002
   TAT-SF1 Elongation factor Binds UsnRNPs Fong and Zhou 2002
   p54nrb Transcription factor In complexes with UsnRNPs Kameoka et al. 2004
   PSF Transcription factor In complexes with UsnRNPs Kameoka et al. 2004
   TLS Transcription factor In complexes with UsnRNPs Kameoka et al. 2004
   CoAA Coactivator hnRNP-like protein Auboeuf et al. 2004b
Regulates alternative splicing
Yeast
   PrP40 Binds phosphoCTD Splicing factor Morris and Greenleaf 2000
   Spt5 Elongation factor Activates splicing Lindstrom et al. 2003


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Source: RNA (2004), 10:1489-1498


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