Hepatitis B virus (HBV) is a small DNA-containing virus with 4 genes, C, …

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Biology Articles » Virology » Molecular analysis of hepatitis B virus "a" determinant in asymptomatic and symptomatic Mexican carriers » Conclusion

Conclusion

- Molecular analysis of hepatitis B virus "a" determinant in asymptomatic and symptomatic Mexican carriers

In conclusion, we report the genotypes of HVB prevalent in symptomatic and asymptomatic patients in Mexico and show that there is more genetic diversity and mutations in the "a" determinant of HBV strains infecting asymptomatic carriers than in symptomatic patients. In HBV strains from our population genotype H and subtype adw4q+ were predominant. The role of viral genotype and subtype, as well as the ethnicity of the host in the determination of the clinical outcome of HBV infection is still unclear, and studies on genotypes infecting populations should help to clarify this issue.