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In this study, the authors evaluated the photoresponsiveness of the circadian system …


Biology Articles » Chronobiology » Light-dark cycle synchronization of circadian rhythm in blind primates » Conclusion

Conclusion
- Light-dark cycle synchronization of circadian rhythm in blind primates

Ours results constitute the first experimental evidence that non-classical retinal photoreceptors can provide photic information to the circadian system of primates and diurnal animals. The blind marmosets may provide an excellent model for the study of photoreception and entrainment in primates. Possible benefits are obvious, such as the development of strategies to solve the problem of synchronization in blind humans or to study retinal degeneration.

 

Competing interests

The author(s) declare that they have no competing interests.

Authors' contributions

MMAS: Participated in all experiments, in the analysis and discussion of the results, and in the writing of the manuscript.

AMA: Participated in all experiments, in the analysis and discussion of the results, and in the writing of the manuscript.

JFA: Participated in all experiments, in the analysis and discussion of the results, and in the writing of the manuscript.

All authors read and approved the final manuscript.

Acknowledgements

We thank Dr. Alexandre Bezerra Gomes for performing the ophthalmoscopic exam in our animals. Supported by grants from CNPq (to JFA and MMAS) and PPq-UFRN (to AMA).


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