Tandem mass spectrometry (Tandem MS or MS-MS) is a major technological
advance in the screening for inherited metabolic diseases.
It has the potential for simultaneous and robust multiple disease
screening using a single analytical technique. It permits the expansion
of screening of many disorders of organic and amino acid metabolism and
fatty acid oxidation disorders. Only few spots of blood on a filter
paper are required to prepare an adequate specimen. The utility and
application of MS-MS has been demonstrated in many countries worldwide.,
This facility is available at NIMHANS, Bangalore and Lal PathLabs, New Delhi.