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Home » Biology Articles » Methods & Techniques » Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately assess beta cell function in clinical studies » Figures

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- Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately assess beta cell function in clinical studies

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Figure 1 The hyperbolic relationship between insulin sensitivity and insulin secretion. Glucose tolerance is bad if an individual is located below the hyperbolic line and good if an individual is located on or above the line. Arrows indicate possible therapeutic approaches to move from the bad to the good area by increasing either insulin sensitivity or secretion.

 figure 1

 

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Figure 2 Scatterplots of insulin sensitivity (measured by euglycemic, hyperinsulinemic clamp) vs the acute insulin responses to arginine at fasting glucose in 71 women, aged 58 years, with normal glucose tolerance (O) (W) vs 37 women, aged 58 years, with impaired glucose tolerance (IGT) (). The regression line is shown for the hyperbolic fit of the data for the groups with normal glucose tolerance. Original data are reported in (15) where the relationship at higher glucose levels is also illustrated.

 

 figure 2

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