This study was conducted to evaluate the immunohistochemical (IHC) expression of interleukin 8 (…

• Abstract
• Background
• Materials and methods
• Results
• Discussion
• Conclusion
• Abbreviations
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Biology Articles » Medicine » Dermatology » Immunohistochemical expression of interleukin 8 in skin biopsies from patients with inflammatory acne vulgaris » Conclusion

Conclusion

- Immunohistochemical expression of interleukin 8 in skin biopsies from patients with inflammatory acne vulgaris

We were able to demonstrate the altered immunoreactivity of IL-8 in IAV compared to normal non lesional skin. An important feature of this study is the strong association between IL-8 IHC expression of endothelial cells and dermal inflammatory response and dermal angiogenesis. Targeted therapy to block IL-8 production may hold promise in limiting the deleterious effects of IL-8-mediated inflammatory response and angiogenesis.