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Figure 1 Patient flow-chart. * All patients who received at least one dose of investigational medication and having at least one follow-up contact.

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Figure 2 Response rates after 7, 14 and 28 days of treatment. Response rates (% of patients with complete recovery or major improvement) at 7, 14 and 28 days after treatment in children and adults. Full-set analysis with last observation carried forward (LOCF) at day 14 and 28. Children n = 659 (homeopathy, 407; conventional, 252) and adults n = 907 (homeopathy, 445; conventional, 462).

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Figure 3 Onset of improvement within the first week. Onset of improvement within the first week of treatment (cumulative percentages of patients that experienced their first improvement). Children n = 659 (homeopathy, 407; conventional, 252) and adults n = 907 (homeopathy, 445; conventional, 462). Full-set analysis values with * p = 0.0448 for children and * p = 0.0001 for adults, using the Chi-square test on data points of the whole curve.

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Figure 4 Main outcome measure – corrections for baseline. Main outcome measure: response to treatment (complete recovery or major improvement) of full-set analysis data at day 14, unadjusted odds ratio's and adjusted odds ratio's for baseline differences with 95% confidence intervals. Between brackets: the number of responders in the homeopathy group and conventional group, respectively. Odds ratio above 1 indicates a better outcome upon homeopathic treatment.

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