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Epidemiological evidence suggests a possible association between chronic exposures to toxigenic molds …


Biology Articles » Toxicology » High Cholesterol Levels And Chronic Exposure To Toxigenic Molds In Damp Buildings: A High Risk For Cardiovascular Diseases And Stroke » Conclusion

Conclusion
- High Cholesterol Levels And Chronic Exposure To Toxigenic Molds In Damp Buildings: A High Risk For Cardiovascular Diseases And Stroke

The structure, synthesis, and utilization of cholesterol and the regulatory processes that prevent over-accumulation and abnormal deposition within the body and the associations with cardiovascular diseases have been reviewed. High cholesterol levels in individuals with chronic exposures to toxigenic molds in damp buildings were observed. Whether the observed cholesterol levels in living under chronic toxigenic molds are related to mycotoxins is yet to be determined. However, based on the findings in the literature and considering the structural disposition of cholesterol that has mechanistically functional affinity to that of mycotoxin, it is predicted that the abnormal cholesterol levels in individuals presenting with chronic toxigenic mold exposures might be related to adverse interaction between cholesterol and mycotoxins. If the prediction is confirmed, then, high cholesterol levels in individuals with chronic exposures to toxigenic molds in damp buildings may lead to a high risk for cardiovascular diseases and stroke.


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