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The present study was designed to investigate the effect of Oroxylum indicum …


Biology Articles » Ethnobiology » Hepatoprotective effect of root bark of Oroxylum indicum on carbon tetrachloride (CCl4) - induced hepatotoxicity in experimental » Conclusion

Conclusion
- Hepatoprotective effect of root bark of Oroxylum indicum on carbon tetrachloride (CCl4) - induced hepatotoxicity in experimental

It is concluded from our study that alcoholic, petroleum ether and n-butanol fractions of root bark of Oroxylum indicum showed significant hepatoprotective activity. The hepatoprotective activity of this plant can be correlated with its antioxidant enzyme activity. Further, with the aid of HPLC based profiling techniques, the hepatoprotective activity could also be linked to a significant extent, to the presence of baicalein, a major flavonoid in n-butanol fraction of this plant. Thus, this plant may serve as a useful adjuvant in several clinical conditions associated with liver damage, which is evident from the results of biochemical assays and histopathological study.  

Acknowledgement:

The authors are thankful to GUJCOST (Gujarat Council on Science and Technology) for financial assistance by providing minor research project scheme


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