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Biology Articles » Genetics » Behavioral Genetics » The Genetics of Schizophrenia » Figures

Figures
- The Genetics of Schizophrenia

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Figure 1.Comparison of a Selected Set of Relatively Well-Established Risk Factors for Schizophrenia, Focusing Mainly on Pre- and Antenatal Factors [6] (abbreviations: CNS, central nervous system; depr, depression; Rh, Rhesus)

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Figure 2.Summary of Genomewide Linkage Studies of Schizophrenia

The x-axis shows the location on the genome, from the telomere of the short arm of Chromosome 1 to the telomere of the long arm of Chromosome 22 (bottom row) along with 303 band chromosomal staining on the second-to-bottom row. The y-axis shows the 27 primary samples that reported first-stage genome scans for schizophrenia (i.e., excluding fine-mapping or partial reports) along with the results of a meta-analysis including most of the primary samples [12] (studies not included are shown with asterisks). Within each row, the height and color of the bars are proportional to the –log10(P-value), and the width of the bar shows the genomic location implicated by a particular sample. A selected set of candidate genes for schizophrenia are also shown. All genomic locations are per the hg16 build (http://genome.ucsc.edu). The physical positions of an inclusive set of the markers showing the best findings in the primary samples were plotted (assuming a confidence interval of ± 10 cM or, if mapping was uncertain, ± 10 megabases; seven markers from the primary samples did not map).

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