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Figure 1 Crohn's disease map of chromosome 6p and the HLA region. The IBD susceptibility locus IBD3 is here defi ned by a 34cM chromosomal bin (6.2), which reached genome wide signifi cance for IBD in the genome scan meta-analysis of van Heel et al[10]. The IBD3 region encompasses the ~ 4MB HLA region shown in detail on the right of the fi gure. White, grey, striped and black boxes show expressed genes, gene candidates, non-coding genes and pseudogenes, respectively. Genes with polymorphisms ssociate with IBD are shown in red. Modifi ed with permission from Shiina et al[61].

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Source: World J Gastroenterol 2006 June 21;12(23):3628-3635
© 2006 The WJG Press. All rights reserved.