Faster, more cost-effective DNA test for crime scenes, disease diagnosis
July 8, 2009 -- Scientists
in Japan are reporting development of a faster, less expensive version
of the fabled polymerase chain reaction (PCR), a DNA test widely used
in criminal investigations, disease diagnosis, biological research and
other applications. The new method could lead to expanded use of PCR in
medicine, the criminal justice system and elsewhere, the researchers
say. Their study is scheduled for the July 15 issue of Analytical Chemistry, a semi-monthly journal.
The scientists describe development and testing of a new PCR method, called the universal QProbe system, that overcomes these problems. Existing PCR processes require several “fluorescent probes” to seek out DNA. QProbe substitutes a single “fluorescent probe” that can detect virtually any target, saving time and cutting costs. The new method also is more specific, accurately detecting DNA even in the presence of unfavorable PCR products in the samples that may interfere with quantification results.
--News release courtesy of American Chemical Society
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