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Anethum has no significant effect on lipid profile, but garlic tablet has …


Biology Articles » Biochemistry » Lipid Biochemistry » Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients » Results

Results
- Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients

Fortunately, all of the patients cooperated well and did not show any adverse effect of these herbal drugs.

Changes of lipid profiles after 6 weeks and results of paired t test are shown in table 2 and 3, respectively. It was found that changes in triglyceride, total cholesterol, LDL-cholesterol, and HDL-cholesterol were significantly different between three groups.

Placebo

Placebo could not improve lipid profile. Triglyceride, total cholesterol, and LDL-cholesterol increased and HDL-cholesterol was reduced. These changes were not meaningful (P-value > 0.05).

Anethum graveolens

Anethum didn't have any beneficial effect on triglyceride (6.0% increase) and HDL-cholesterol (3.1% reduction). It could reduce total cholesterol by 0.4 % and LDL-cholesterol by 6.3 %, but these reductions were not significant statistically (P-value: .828, .210, respectively).

Garlic

At the end of the six-week intervention period, it was fond that changes in triglyceride, total cholesterol, LDL-cholesterol, and HDL-cholesterol were significantly different from other groups. The mean total cholesterol concentration dropped in the garlic group by 26.82 mg/dl (P-value: .000.) Similarly, LDL-cholesterol was reduced in this group by 22.18 mg/dl (P-value: .000). Surprisingly, HDL-cholesterol was increased by 10.02 mg/dl (P-value: .000). Although triglyceride dropped by 13.72 mg/dl but this was not meaningful (P-value: .222).


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