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The authors describe a novel lentiviral packaging system in which not only …


Biology Articles » Virology » Design of a trans protease lentiviral packaging system that produces high titer virus » Conclusion

Conclusion
- Design of a trans protease lentiviral packaging system that produces high titer virus

Here we presented a novel "super-split" lentiviral packaging system with the potential to be used for gene therapy applications. Since this system incorporates many new safety features while using a less cytotoxic mutant PR, it also presents new opportunities to develop better high titer HIV packaging cell lines.

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