These isoenzymes are a major determinant of the pharmacokinetic behavior of numerous …

• Abstract
• Introduction
• Cytochrome P450 isoenzymes (CYPs)
• Genetic polymorphism
• Drug Drug interaction
• Enzyme induction
• Enzyme inhibiton
• CYP1A 2, CYP2C 9, CYP2C 19, CYP2D 6, CYP2E 1 & CYP3A 4
• Conclusion
• References
• Figure
• Tables

An understanding of unique function and characteristics of CYP enzymes is must for the physicians as they face various drug drug interactions related morbidity in their routine practice and are a part to it too. Here, comes the role of clinical pharmacologists to provide clinicians with updated information regarding drug metabolizing enzymes and drug interactions caused by them in easy to comprehend(tabular, hand outs, booklets etc) forms so that they can better anticipate and manage drug drug interactions.