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Figure 1. Age vs unilateral testicular volume in adolescent patients with testicular cancer (gray squares), malignant Hodgkin lymphoma (black circles), leukemia (gray triangle), bone cancer (gray diamond), and other types of cancer (white triangle). Gray lines represent the mean and 95% confidence intervals of normal testicular volumes during normal adolescence and are taken from Zachmann et al (1974).

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Figure 2. Unilateral testicular volume vs (a) serum testosterone and (b) sperm counts in adolescents with testicular cancer (gray squares), malignant Hodgkin lymphoma (black circles), leukemia (gray triangle), bone cancer (gray diamond), and other types of cancer (white triangle) prior to cryopreservation. Regression lines were calculated on the basis of all points shown in the graphs, regardless of the underlying disease, and are shown as black lines. Horizontal dashed gray lines represent the lower normal limit (testosterone and sperm count).

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Source: Journal of Andrology, Vol. 25, No. 4, July/August 2004.