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This analysis explains how cell size is maintained through a combination of …


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Biology Articles » Cell biology » Control and maintenance of mammalian cell size » Table

Table
- Control and maintenance of mammalian cell size

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Table 1 Analysis of linear and exponential growth by comparing long-term and short-term isotope incorporation.

LINEAR GROWTH EXPONENTIAL GROWTH
Cell size Size increase Inc/size Cell age Cell size Size increase Inc/size
1 0.1 0.100 0 1.00 0.07 0.072
1.1 0.1 0.091 0.1 1.07 0.08 0.072
1.2 0.1 0.083 0.2 1.15 0.08 0.072
1.3 0.1 0.077 0.3 1.23 0.09 0.072
1.4 0.1 0.071 0.4 1.32 0.09 0.072
1.5 0.1 0.067 0.5 1.41 0.10 0.072
1.6 0.1 0.063 0.6 1.52 0.11 0.072
1.7 0.1 0.059 0.7 1.62 0.12 0.072
1.8 0.1 0.056 0.8 1.74 0.12 0.072
1.9 0.1 0.053 0.9 1.87 0.13 0.072
2 1 2.00

The center, bold-faced, column lists the cell ages from 0 to 1.0. At the left the linear increase of mass is related to the absolute increase in mass per interval (0.1 each interval for linear increase in mass during division cycle), and the ratio of incorporation per extant cell mass is given in the third column (0.1 to 0.053). Similar results for exponential growth except the mass increase per interval goes from 0.07 at the start of the division cycle to 0.13 at the end. The ratio of incorporation per extant mass in the right-most column is thus constant.

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Source: BMC Cell Biol. 2004; 5: 35.

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