Use of modern miniature cryoprobes for cryoablation of bone tissue seems to …

• Abstract
• Background
• Methods
• Results
• Discussion
• Conclusion
• References
• Figures

In conclusion the use of modern miniature cryoprobes for cryoablation of bone tissue seems to be a gentle method, and the complications reported for earlier systems did not occur in this study. Therefore, this cryosurgical technique has a pontential in human subjects and could be usefull either to complement conventional resections, or else as a minimally invasive alternative procedure.


Competing interests

The author(s) declare that they have no competing interests.


Authors' contributions

FP and PM carried out the operations and drafted the manuscript. MB and TK carried out the hole perioperativ treatment of the animals and the monitoring throughout the intra- and perioperative phase. HE performed the histological investigations. JHF participated in the design of the study and performed the statistical analysis. PE conceived of the study, and participated in its design and coordination. All authors read and approved the final manuscript.


Acknowledgements

This study was performed with approval of the local animal care committee and supported by the Köln Fortune Programm/Faculty of Medicine, University of Cologne, Germany.