The purpose of this review is to discuss the methodologies being developed …

• Abstract
• Introduction
• GH Abuse
• Manipulation of the GH-IGF Axis
• Methodologies for Detecting GH
• Conclusion
• References
• Figures
• Table

Conclusion 

Anecdotal evidence suggests that GH has been widely abused by sportsmen and -women for the last 20 years because of its anabolic and lipolytic properties. Recent major advances in methodologies to detect GH have led to the introduction of testing for GH for the first time at the Athens Olympic Games.

Acknowledgments

The GH-2004 project is funded through grants from the US Anti-Doping Agency and World Anti-Doping Agency.

Footnotes
 
¹ Nonstandard abbreviations: GH, growth hormone; WADA, World Anti-Doping Agency; GC, gas chromatography; rhGH, recombinant human growth hormone; IGF-I, insulin-like growth factor-I; IGFBP, insulin-like growth factor–binding protein; IFA, immunofunctional assay; GHBP, growth hormone–binding protein; P-III-P, procollagen III terminal peptide; PICP, C-terminal propeptide of collagen type I; and ICTP, C-terminal cross-linked telopeptide of type I collagen.