Tables

- The atherogenic and metabolic impact of non-HDL cholesterol versus other lipid sub-components among non-diabetic and diabetic Saudis

Table 1

Clinical and Metabolic characteristics of subjects
Variable	Non-Diabetics	Diabetics	P-Value

N	462	271
Age (years)	45.03 ± 11.52	52.73 ± 11.45	0.000
Systolic BP (mmHg)	120.57 ± 18.23	130.17 ± 19.74	0.000
Diastolic BP (mmHg)	78.15 ± 11.65	82.27 ± 10.71	0.000
BMI (kg/m²)	28.91 ± 6.07	30.15 ± 6.62	0.011
LDL (mmol/L)	3.63 ± 1.31	3.47 ± 1.55	0.17
HDL (mmol/L)	0.91 ± 0.45	0.80 ± 0.32	0.000
Non-HDL (mmol/L)	4.36 ± 1.47	4.67 ± 1.54	0.009
Total Cholesterol (mmol/Ll)	5.26 ± 1.39	5.52 ± 1.74	0.04
Triglycerides (mmol/L)	1.74 ± 1.06	2.63 ± 1.37	0.000
* Data are presented as mean ± SD; p-value significant at
Al-Daghri et al. Lipids in Health and Disease 2007 6:9 doi:10.1186/1476-511X-6-9

Table 2

Relative risk of probable coronary heart disease for various cut-off values of lipids
	Non-Diabetic	Diabetic

N	465	271
Probable CHD	99	114
LDL cholesterol (mmol/L)
	0.87 (0.70–1.09)	0.95 (0.86–1.05)
2.59–3.34	0.99 (0.76–1.30)	1.03 (0.91–1.17)
≥ 3.35	1.05 (0.92–1.19)	1.13 (0.91–1.39)
Non-HDL- cholesterol (mmol/L)
	0.94 (0.85–1.04)	0.95 (0.74–1.22)
3.35–4.13	0.86 (0.67–1.09)	1.06 (0.93–1.21)
≥ 4.14	1.01 (0.92–1.11)	1.15 (0.93–1.42)
Total Cholesterol (mmol/L)
	1.02 (0.93–1.12	0.81 (0.65–1.00)
5.17–6.19	0.93 (0.84–1.03)	1.11 (0.86–1.44)
≥ 6.20	1.09 (0.95–1.24)	1.18 (0.91–1.53)
HDL Cholesterol (mg/dl)
≥ 1.55	0.85 (0.76–0.96)	1.76 (0.56–5.47)
1.03–1.54	1.10 (0.96–1.25)	1.37 (0.98–1.91)
	0.99 (0.89–1.10)	0.70 (0.51–0.97)
Triglycerides (mg/dl)
	0.79 (0.70–0.89)	0.96 (0.75–1.23)
1.69–2.25	0.98 (0.86–1.11)	1.20 (0.86–1.67)
≥ 2.26	1.05 (0.93–1.19)	0.94 (0.75–1.46)
*Data presented as Relative risk (95% Confidence interval)
Al-Daghri et al. Lipids in Health and Disease 2007 6:9 doi:10.1186/1476-511X-6-9

Logistic regression analysis using probable CHD as a dependent variable and the various lipids as independent variables
Non-Diabetics

Predictor	β	SE	Odds-Ratio	95% Confidence Interval	P-Value

Non-HDL	1.06	0.49	2.89	1.10–7.58	0.03
HDL	-0.19	0.27	0.83	0.49–1.40	0.48
LDL	-0.65	0.48	0.52	0.21–1.32	0.17
Triglycerides	0.07	0.25	1.07	0.65–1.76	0.79
Total Cholesterol	-0.36	0.29	0.69	0.39–1.23	0.21
β – Beta; SE – standard error
Al-Daghri et al. Lipids in Health and Disease 2007 6:9 doi:10.1186/1476-511X-6-9

Logistic regression analysis using probable CHD as a dependent variable and the various lipids as independent variables
Diabetics

Predictor	β	SE	Odds-Ratio	95% Confidence Interval	P-Value

Non-HDL	-0.26	0.51	0.77	0.28–2.01	0.61
HDL	-0.66	0.33	0.52	0.27–0.99	0.05
LDL	0.16	0.47	1.18	0.47–2.93	0.73
Triglycerides	0.09	0.31	1.09	0.59–2.01	0.78
Total Cholesterol	0.31	0.35	1.36	0.68–2.71	0.39
β – Beta; SE – standard error
Al-Daghri et al. Lipids in Health and Disease 2007 6:9 doi:10.1186/1476-511X-6-9

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