Association between molecular markers linked to the Leptin gene and weight gain in postpartum beef cows
Sabrina Esteves Matos AlmeidaI; Erik Amazonas de AlmeidaI; Gustavo TerraII; Jairo Pereira NevesIII; Paulo Bayard Dias GonçalvesII; Tania de Azevedo WeimerI, IV, 1
IUniversidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brasil
IIUniversidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brasil
IIIUniversidade de Brasília (UNB), Brasília, DF, Brasil
IVUniversidade Luterana do Brasil (ULBRA), Canoas, RS. Autor para correspondência: Duque de Caxias, 910/101, 90010-280, Porto Alegre, RS, Brasil.
Three short tandem repeats (STRs), BMS1074, BM1500, IDVGA-51, and three single nucleotide polymorphisms (SNPs), LEPSau3AI (A/B), LEPSau3AI (+/-) and LEPKpn2I linked to the LEP gene were investigated to verify associations with productive performance in postpartum cows of two beef cattle breeds, Aberdeen Angus (AA, n=98) and Charolais (C, n=83). After polymerase chain reaction, STRs were analyzed by vertical electrophoresis and SNPs in agarose gel after endonucleases cleavage. In AA herd 79% of BMS1074*151 carriers had a lower average daily weight gain (ADG) when compared with the population mean daily weight gain (103g), while 62% of BMS1074*151 non-carriers presented a higher ADG (P<0.01); AA animals with at least one BMS1074*151 allele showed a ADG about 159g lower than that of other animals (P<0.01). In both herds, carriers of the BM1500*136 allele presented higher ADG (about 75g day-1 higher in AA, P<0.05, and 96g day-1 in C, P<0.10); animals with one BM1500*136 allele had about a 3-fold higher chance of having a higher ADG than non-cariers, in both populations.
Key words: Leptin, STRs, SNPs, beef cattle, weight gain, post-partum.
Cienc. Rural vol.37 no.1 Santa Maria Jan./Feb. 2007. Open Access Article.