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These findings indicate that IB cells receive less GABAA-mediated inhibitory input and …


Biology Articles » Anatomy & Physiology » Anatomy, Physiology, and Synaptic Responses of Rat Layer V Auditory Cortical Cells and Effects of Intracellular GABAA Blockade » Table 1

Table 1
- Anatomy, Physiology, and Synaptic Responses of Rat Layer V Auditory Cortical Cells and Effects of Intracellular GABAA Blockade

Table 1. Comparisons of IB and RS cell anatomy, intrinsic physiological properties, and synaptic responses

  RS IB

Vrest, mV  -66.2 ± 4.0  -66.4 ± 4.0
Rin, MOmega 49.2 ± 14.7 30.7 ± 8.6*
First spike half-width, ms 0.93 ± 0.25 0.72 ± 0.14*
Fifth spike half-width, ms 1.23 ± 0.46dagger 0.76 ± 0.15*
EPSP latency, ms 2.8 ± 1.6 2.5 ± 1.6
GABAA present 50 of 56 16 of 36Dagger
GABAB present 50 of 56 1 of 36Dagger
IPSP latency, ms 4.4 ± 1.7§ 3.5 ± 1.1
Fast IPSP (GABAA) reversal, mV  -60.7 ± 3.6  -62.1 ± 5.0
Suprathreshold at rest 16 of 56 27 of 36Dagger
Soma size, µm2 145 ± 21 212 ± 22*
Apical dendrite diameter    
  50 µm 2.2 ± 0.4 3.8 ± 0.7*
  200 µm 2.0 ± 1.3 3.3 ± 0.6*
  400 µm 0.8 ± 0.4 2.7 ± 0.4*
Branches from apical dendrite    
  Layer V 4.8 ± 2.6 7.9 ± 4.8
  Layer IV 3.4 ± 1.8 10.0 ± 3.3*
  Layer III 0.8 ± 0.8 5.7 ± 1.9*
  Layer II 0.1 ± 0.3 0.8 ± 0.9*
Total branches in layer I 0.6 ± 1.3 13.1 ± 3.4*

Values are means ± SD. Number of RS neurons is 67 and IB neurons is 39. RS, regular spiking; IB, intrinsic bursting; EPSP, excitatory postsynaptic potential; IPSP, inhibitory postsynaptic potential. * Statistically significant difference of at least P < 0.05 using a 2 sample t-test when comparing the RS cell value to the IB cell value. dagger Statistically significant (P < 0.05) for the comparison of RS cell 1st and 5th spikes. Dagger Statistical significance of at least P < 0.05 using a chi2 test when comparing the RS to the IB cell numbers. § EPSP latencies were significantly shorter (P < 0.01) than IPSP latencies in both IB and RS cells.

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