Schizophrenia is a relatively common, chronic, and frequently devastating neuropsychiatric disorder, affecting …

• Summary
• Introduction
• Molecular Genetics of Schizophrenia
• Environmental Risk Factors for Schizophrenia
• The Neurotransmitter Hypothesis of Schizophrenia
• Neurodevelopmental Hypothesis of Schizophrenia
• Brain Imaging Studies of Schizophrenia
• Developing Novel Antipsychotic Drugs
• Future Directions
• Conclusion
• Acknowledgements
• References
• Tables

Acknowledgments

This work was supported in part by the UNC Schizophrenia Research Center, an NIMH Silvio O. Conte Center for the Neuroscience of Mental Disorders (MH064065), and the Foundation of Hope of Raleigh North Carolina. The authors would like to acknowledge the support of Janssen Pharmaceutical K.K. (Japan) in preparing this manuscript.