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Home » Biology Articles » Neurobiology » Neurobiology of Diseases & Aging » Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use » References

References
- Actions of Caffeine in the Brain with Special Reference to Factors That Contribute to Its Widespread Use

  • American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders Revised 3rd ed. American Psychiatric Association, Washington, DC..
  • American Psychiatric Association (1992) Diagnostic and Statistical Manual of Mental Disorders 4th ed. American Psychiatric Association, Washington, DC..
  • American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders Revised 4th ed. American Psychiatric Association, Washington, DC..
  • Aldridge A, Aranda JV and Neims AH (1979) Caffeine metabolism in the newborn. Clin Pharmacol Ther  25: 447-453[Medline].
  • Aldridge A, Bailey J and Neims AH (1981) The disposition of caffeine during and after pregnancy. Semin Perinatol  5: 310-314[Medline].
  • Ammon HP (1991) Biochemical mechanism of caffeine tolerance. Arch Pharm (Weinheim)  324: 261-267[Medline].
  • Andén NE and Jackson DM (1975) Locomotor activity stimulation in rats produced by dopamine in the nucleus accumbens: potentiation by caffeine. J Pharm Pharmacol  27: 666-670[Medline].
  • Anderson KJ and Revelle W (1982) Impulsivity, caffeine, and proofreading: A test of the Easterbrook hypothesis. J Exp Psychol Hum Percept Perform  8: 614-624[Medline].
  • Andiné P, Rudolphi KA, Fredholm BB and Hagberg H (1990) Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia. Br J Pharmacol  100: 814-818[Medline].
  • Arai A, Kessler M and Lynch G (1990) The effects of adenosine on the development of long-term potentiation. Neurosci Lett  119: 41-44[Medline].
  • Aranda JV, Collinge JM, Zinman R and Watters G (1979) Maturation of caffeine elimination in infancy. Arch Dis Child  54: 946-949[Abstract].
  • Aranda JV, Gorman W, Bergsteinsson H and Gunn T (1977) Efficacy of caffeine in treatment of apnea in the low-birth-weight infant. J Pediatr  90: 467-472[Medline].
  • Aranda JV, MacLeod SM, Renton KW and Eade NR (1974) Hepatic microsomal drug oxidation and electron transport in newborn infants. J Pediatr  85: 534-542[Medline].
  • Arbeit ML, Nicklas TA, Frank GC, Webber LS, Miner MH and Berenson GS (1988) Caffeine intakes of children from a biracial population: The Bogalusa Heart Study. J Am Diet Assoc  88: 466-471[Medline].
  • Arch JR and Newsholme EA (1978) The control of the metabolism and the hormonal role of adenosine. Essays Biochem  14: 82-123[Medline].
  • Arnaud MJ (1976) Identification, kinetic and quantitative study of [2-14C] and [1-Me-14C]caffeine metabolites in rat's urine by chromatographic separations. Biochem Med  16: 67-76[Medline].
  • Arnaud MJ (1985) Comparative metabolic disposition of [1-Me14C]caffeine in rats, mice, and Chinese hamsters. Drug Metab Dispos  13: 471-478[Abstract].
  • Arnaud MJ (1987) The pharmacology of caffeine. Prog Drug Res  31: 273-313[Medline].
  • Arnaud MJ (1993) Metabolism of caffeine and other components of coffee, in Caffeine, Coffee and Health (Garattini S ed) pp 43-95, Raven Press, New York.
  • Arnaud MJ and Welsch C (1982) Theophylline and caffeine metabolism in man, in Theophylline and Other Methylxanthines (Reitbrock N, Woodcock BG andStaib AH eds) pp 135-148, Friedr. Vieweg and Sons, Zurich.
  • Arushanian EB and Belozertsev YB (1978) The effect of amphetamine and caffeine on neuronal activity in the neocortex of the cat. Neuropharmacology  17: 1-6[Medline].
  • Atkinson J and Enslen M (1976) Self-administration of caffeine by the rat. Arzneimittelforschung  26: 2059-2061[Medline].
  • Baldwin HA, Johnston AL and File SE (1989) Antagonistic effects of caffeine and yohimbine in animal tests of anxiety. Eur J Pharmacol  159: 211-215[Medline].
  • Ballarin M, Fredholm BB, Ambrosio S and Mahy N (1991) Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism. Acta Physiol Scand  142: 97-103[Medline].
  • Ballarin M, Reiriz J, Ambrosio S and Mahy N (1995) Effect of locally infused 2-chloroadenosine, an A1 receptor agonist, on spontaneous and evoked dopamine release in rat neostriatum. Neurosci Lett  185: 29-32[Medline].
  • Barone J and Roberts H (1984) Human consumption of caffeine, in Caffeine: Perspectives from Recent Research (Dews PB ed) pp 59-73, Springer-Verlag, Heidelberg.
  • Barone JJ and Roberts HR (1996) Caffeine consumption. Food Chem Toxicol  34: 119-129[Medline].
  • Barraco RA, Martens KA, Parizon M and Normile HJ (1993) Adenosine A2a receptors in the nucleus accumbens mediate locomotor depression. Brain Res Bull  31: 397-404[Medline].
  • Bättig K, Buzzi R, Martin JR and Feierabend JM (1984) The effects of caffeine on physiological functions and mental performance. Experientia  40: 1218-1223[Medline].
  • Bättig K and Welzl H (1993) Psychopharmacological profile of caffeine, in Caffeine, Coffee and Health (Garattini S ed) pp 213-253, Raven Press, New York.
  • Bedingfield JB, King DA and Holloway FA (1998) Cocaine and caffeine: Conditioned place preference, locomotor activity, and additivity. Pharmacol Biochem Behav  61: 291-296[Medline].
  • Benington JH, Kodali SK and Heller HC (1995) Stimulation of A1 adenosine receptors mimics the electroencephalographic effects of sleep deprivation. Brain Res  692: 79-85[Medline].
  • Benowitz NL, Hall SM and Modin G (1989) Persistent increase in caffeine concentrations in people who stop smoking. BMJ  298: 1075-1076[Medline].
  • Benowitz NL, Jacob P, 3rd, Mayan H and Denaro C (1995) Sympathomimetic effects of paraxanthine and caffeine in humans. Clin Pharmacol Ther  58: 684-691[Medline].
  • Bertorelli R, Ferri N, Adami M and Ongini E (1996) Effects of selective agonists and antagonists for A1 and A2A adenosine receptors on sleep-waking patterns in rats. Drug Dev Res  37: 65-72.
  • Bevan MD, Clarke NP and Bolam JP (1997) Synaptic integration of functionally diverse pallidal information in the entopeduncular nucleus and subthalamic nucleus in the rat. J Neurosci  17: 308-324[Abstract/Free Full Text].
  • Bhat RV, Cole AJ and Baraban JM (1992) Chronic cocaine treatment suppresses basal expression of zif268 in rat forebrain: in situ hybridization studies. J Pharmacol Exp Ther  263: 343-349[Abstract/Free Full Text].
  • Bickel WK, DeGrandpre RJ and Higgins ST (1995) The behavioral economics of concurrent drug reinforcers: a review and reanalysis of drug self-administration research. Psychopharmacology  118: 250-259[Medline].
  • Bickel WK, Hughes JR, DeGrandpre RJ, Higgins ST and Rizzuto P (1992) Behavioral economics of drug self-administration: IV. The effects of response requirement on the consumption of and interaction between concurrently available coffee and cigarettes. Psychopharmacology  107: 211-216[Medline].
  • Bickford PC, Fredholm BB, Dunwiddie TV and Freedman R (1985) Inhibition of Purkinje cell firing by systemic administration of phenylisopropyl adenosine: effect of central noradrenaline depletion by DSP4. Life Sci  37: 289-297[Medline].
  • Biggs TA and Myers RD (1997) Adenosine A1 receptor antisense infused in striatum of rats: actions on alcohol-induced locomotor impairment, blood alcohol, and body temperature. Alcohol  14: 617-621[Medline].
  • Birkett DJ and Miners JO (1991) Caffeine renal clearance and urine caffeine concentrations during steady state dosing. Implications for monitoring caffeine intake during sports events. Br J Clin Pharmacol  31: 405-408[Medline].
  • Blanchard J and Sawers SJ (1983a) The absolute bioavailability of caffeine in man. Eur J Clin Pharmacol  24: 93-98[Medline].
  • Blanchard J and Sawers SJ (1983b) Comparative pharmacokinetics of caffeine in young and elderly men. J Pharmacokinet Biopharm  11: 109-126[Medline].
  • Bona E, Ådén U, Fredholm BB and Hagberg H (1995) The effect of long term caffeine treatment on hypoxic-ischemic brain damage in the neonate. Pediatr Res  38: 312-318[Abstract].
  • Bonati M, Latini R, Galletti F, Young JF, Tognoni G and Garattini S (1982) Caffeine disposition after oral doses. Clin Pharmacol Ther  32: 98-106[Medline].
  • Bonati M, Latini R, Tognoni G, Young JF and Garattini S (1984-5) Interspecies comparison of in vivo caffeine pharmacokinetics in man, monkey, rabbit, rat and mouse. Drug Metab Rev 15:1355-1383.
  • Bonci A and Williams JT (1996) A common mechanism mediates long-term changes in synaptic transmission after chronic cocaine and morphine. Neuron  16: 631-639[Medline].
  • Bonnet MH and Arand DL (1992) Caffeine use as a model of acute and chronic insomnia. Sleep  15: 526-536[Medline].
  • Bonnet MH and Arand DL (1996) Metabolic rate and the restorative function of sleep. Physiol Behav  59: 777-782[Medline].
  • Boulenger JP, Salem N, Jr, Marangos PJ and Uhde TW (1987) Plasma adenosine levels: measurement in humans and relationship to the anxiogenic effects of caffeine. Psychiatry Res  21: 247-255[Medline].
  • Boulenger JP, Uhde TW, Wolff EA and Post RM (1984) Increased sensitivity to caffeine in patients with panic disorders. Arch Gen Psychiatry  41: 1067-1071[Abstract].
  • Brauer LH, Buican B and de Wit H (1994) Effects of caffeine deprivation on taste and mood. Behav Pharmacol  5: 111-118[Medline].
  • Brazier JL, Ritter J, Berland M, Khenfer D and Faucon G (1983) Pharmacokinetics of caffeine during and after pregnancy. Dev Pharmacol Ther  6: 315-322[Medline].
  • Breiter HC, Gollub RL, Weisskoff RM, Kennedy DN, Makris N, Berke JD, Goodman JM, Kantor HL, Gastfriend DR, Riorden JP, Mathew RT, Rosen BR and Hyman SE (1997) Acute effects of cocaine on human brain activity and emotion. Neuron  19: 591-611[Medline].
  • Brockwell NT, Eikelboom R and Beninger RJ (1991) Caffeine-induced place and taste conditioning: production of dose-dependent preference and aversion. Pharmacol Biochem Behav  38: 513-517[Medline].
  • Broughton R and Roberts J (1985) A survey of subjective sleep measures and performance in working adults. Sleep Res  14: 89.
  • Brown CR and Benowitz NL (1989) Caffeine and cigarette smoking: behavioral, cardiovascular, and metabolic interactions. Pharmacol Biochem Behav  34: 565-570[Medline].
  • Brown SJ, Gill R, Evenden JL, Iversen SD and Richardson PJ (1991) Striatal A2 receptor regulates apomorphine-induced turning in rats with unilateral dopamine denervation. Psychopharmacology Ser (Berl)  103: 78-82.
  • Bruce M and Lader M (1986) Caffeine: Clinical and experimental effects in humans. Hum Psychopharmacol  1: 63-82.
  • Bruce MS, Scott NR, Shine P and Lader M (1991) Caffeine withdrawal: A contrast of withdrawal symptoms in normal subjects who have abstained from caffeine for 24 hours and for 7 days. J Psychopharmacol  5: 129-134.
  • Brundege JM and Dunwiddie TV (1995) The role of acetate as a potential mediator of the effects of ethanol in the brain. Neurosci Lett  186: 214-218[Medline].
  • Budney AJ, Higgins ST, Hughes JR and Bickel WK (1993) Nicotine and caffeine use in cocaine-dependent individuals. J Subst Abuse  5: 117-130[Medline].
  • Caine SB and Koob GF (1993) Modulation of cocaine self-administration in the rat through D-3 dopamine receptors. Science  260: 1814-1816[Abstract/Free Full Text].
  • Calabresi P, Lacey MG and North RA (1989) Nicotinic excitation of rat ventral tegmental neurones in vitro studied by intracellular recording. Br J Pharmacol  98: 135-140[Medline].
  • Cameron OG, Modell JG and Hariharan M (1990) Caffeine and human cerebral blood flow: A positron emission tomography study. Life Sci  47: 1141-1146[Medline].
  • Carlezon WA, Jr and Wise RA (1996) Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortex. J Neurosci  16: 3112-3122[Abstract/Free Full Text].
  • Carmichael FJ, Israel Y, Crawford M, Minhas K, Saldivia V, Sandrin S, Campisi P and Orrego H (1991) Central nervous system effects of acetate: Contribution to the central effects of ethanol. J Pharmcol Exp Ther  259: 403-408[Abstract/Free Full Text].
  • Carmichael FJ, Saldivia V, Varghese GA, Israel Y and Orrego H (1988) Ethanol-induced increase in portal blood flow: Role of acetate and A1 and A2 adenosine receptors. Am J Physiol  255: G417-G423[Abstract/Free Full Text].
  • Carney JM (1982) Effects of caffeine, theophylline and theobromine on scheduled controlled responding in rats. Br J Pharmacol  75: 451-454[Medline].
  • Carney JM, Holloway FA and Modrow HE (1985) Discriminative stimulus properties of methylxanthines and their metabolites in rats. Life Sci  36: 913-920[Medline].
  • Carrier O, Pons G, Rey E, Richard MO, Moran C, Badoual J and Olive G (1988) Maturation of caffeine metabolic pathways in infancy. Clin Pharmacol Ther  44: 145-151[Medline].
  • Carroll ME, Hagen EW, Asencio M and Brauer LH (1988) Behavioral dependence on caffeine and phencyclidine in rhesus monkeys: interactive effects. Pharmacol Biochem Behav  31: 927-932[Medline].
  • Carter AJ, O'Connor WT, Carter MJ and Ungerstedt U (1995) Caffeine enhances acetylcholine release in the hippocampus in vivo by a selective interaction with adenosine A1 receptors. J Pharmacol Exp Ther  273: 637-642[Abstract/Free Full Text].
  • Casas M, Ferré S, Cobos A, Grau JM and Jané F (1989) Relationship between rotational behaviour induced by apomorphine and caffeine in rats with unilateral lesion of the nigrostriatal pathway. Neuropharmacology  28: 407-409[Medline].
  • Chagoya de Sanchez V (1995) Circadian variations of adenosine and of its metabolism: Could adenosine be a molecular oscillator for circadian rhythms? Can J Physiol Pharmacol  73: 339-355[Medline].
  • Chagoya de Sanchez V, Hernandez Munoz R, Suarez J, Vidrio S, Yanez L and Diaz Munoz M (1993) Day-night variations of adenosine and its metabolizing enzymes in the brain cortex of the rat: Possible physiological significance for the energetic homeostasis and the sleep-wake cycle. Brain Res  612: 115-121[Medline].
  • Chait LD and Griffiths RR (1983) Effects of caffeine on cigarette smoking and subjective response. Clin Pharmacol Ther  34: 612-622[Medline].
  • Chait LD and Johanson CE (1988) Discriminative stimulus effects of caffeine and benzphetamine in amphetamine-trained volunteers. Psychopharmacology  96: 302-308[Medline].
  • Chang PP, Ford DE, Mead LA, Cooper-Patrick L and Klag MJ (1997) Insomnia in young men and subsequent depression: The Johns Hopkins Precursors Study. Am J Epidemiol  146: 105-114[Abstract/Free Full Text].
  • Charney DS, Galloway MP and Heninger GR (1984) The effects of caffeine on plasma MHPG, subjective anxiety, autonomic symptoms and blood pressure in healthy humans. Life Sci  35: 135-144[Medline].
  • Charney DS, Heninger GR and Jatlow PI (1985) Increased anxiogenic effects of caffeine in panic disorders. Arch Gen Psychiatry  42: 233-243[Abstract].
  • Chavez-Noriega LE and Stevens CF (1994) Increased transmitter release at excitatory synapses produced by direct activation of adenylate cyclase in rat hippocampal slices. J Neurosci  14: 310-317[Abstract].
  • Cherek DR, Steinberg JL and Brauchi JT (1983) Effects of caffeine on human aggressive behavior. Psychiatry Res  8: 137-145[Medline].
  • Chergui K, Nomikos GG, Mathé JM, Gonon F and Svensson TH (1996) Burst stimulation of the medial forebrain bundle selectively increase Fos-like immunoreactivity in the limbic forebrain of the rat. Neuroscience  72: 141-156[Medline].
  • Chergui K, Suaud-Chagny MF and Gonon F (1994) Nonlinear relationship between impulse flow, dopamine release and dopamine elimination in the rat brain in vivo. Neuroscience  62: 641-645[Medline].
  • Chergui K, Svenningsson P, Nomikos GG, Gonon F, Fredholm BB and Svensson TH (1997) Increased expression of NGFI-A mRNA in the rat striatum following burst stimulation of the medial forebrain bundle. J Neurosci  9: 2370-2382.
  • Chern Y, Lai HL, Fong JC and Liang Y (1993) Multiple mechanisms for desensitization of A2a adenosine receptor-mediated cAMP elevation in rat pheochromocytoma PC12 cells. Mol Pharmacol  44: 950-958[Abstract].
  • Choi OH, Shamim MT, Padgett WL and Daly JW (1988) Caffeine and theophylline analogues: Correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors. Life Sci  43: 387-398[Medline].
  • Chung WG and Cha YN (1997) Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes. Biochem Biophys Res Commun  235: 685-688[Medline].
  • Cines BM and Rozin P (1982) Some aspects of the liking for hot coffee and coffee flavor. Appetite  3: 23-34[Medline].
  • Clark M and Dar MS (1991) In vitro autoradiographic evidence for adenosine modulation of ethanol-induced motor disturbances in rats. Alcohol Alcohol Suppl  1: 203-206[Medline].
  • Cole AJ, Bhat RV, Patt C, Worley PF and Baraban JM (1992) D1 dopamine receptor activation of multiple transcription factor genes in rat striatum. J Neurochem  58: 1420-1426[Medline].
  • Cole DG and Di Figlia M (1994) Reserpine increases Fos activity in the rat basal ganglia via a quinpirole-sensitive mechanism. Neuroscience  60: 115-123[Medline].
  • Collins RJ, Weeks JR, Cooper MM, Good PI and Russell RR (1984) Prediction of abuse liability of drugs using IV self-administration by rats. Psychopharmacology  82: 6-13[Medline].
  • Colton T, Gosselin RE and Smith RP (1968) The tolerance of coffee drinkers to caffeine. Clin Pharmacol Ther  9: 31-39[Medline].
  • Comer SD, Haney M, Foltin RW and Fischman MW (1997) Effects of caffeine withdrawal on humans living in a residential laboratory. Exp Clin Psychopharmacol  5: 399-403.[Medline]
  • Conlay LA, Conant JA, deBros F and Wurtman R (1997) Caffeine alters plasma adenosine levels. Nature  389: 136[Medline].
  • Cook CE, Tallent CR, Amerson EW, Myers MW, Kepler JA, Taylor GF and Christensen HD (1976) Caffeine in plasma and saliva by a radioimmunoassay procedure. J Pharmacol Exp Ther  199: 679-686[Abstract/Free Full Text].
  • Couturier EG, Laman DM, van Duijn MA and van Duijn H (1997) Influence of caffeine and caffeine withdrawal on headache and cerebral blood flow velocities. Cephalalgia  17: 188-190[Medline].
  • Cunha RA, Johansson B, Constantino MD, Sebastiao AM and Fredholm BB (1996) Evidence for high-affinity binding sites for the adenosine A2A receptor agonist [3H] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors. Naunyn-Schmiedebergs Arch Pharmacol  353: 261-271[Medline].
  • Curatolo PW and Robertson D (1983) The health consequences of caffeine. Ann Intern Med  98: 641-653[Medline].
  • Curless R, French JM, James OF and Wynne HA (1993) Is caffeine a factor in subjective insomnia of elderly people? Age Ageing  22: 41-45[Abstract/Free Full Text].
  • Daly JW (1993) Mechanism of action of caffeine, in Caffeine, Coffee, and Health (Garattini S ed) pp 97-150, Raven Press, New York.
  • Daly JW, Padgett WL, Secunda SI, Thompson RD and Olsson RA (1993) Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors. Pharmacology  46: 91-100[Medline].
  • D'Amicis A and Viani R (1993) The consumption of coffee, in Caffeine, Coffee and Health (Garattini S ed) pp 1-16, Raven Press, New York.
  • Dar MS (1990) Central adenosinergic system involvement in ethanol-induced motor incoordination in mice. J Pharmacol Exp Ther  255: 1202-1209[Abstract/Free Full Text].
  • Dar MS and Clark M (1992) Tolerance to adenosine's accentuation of ethanol-induced motor incoordination in ethanol-tolerant mice. Alcohol Clin Exp Res  16: 1138-1146[Medline].
  • Dasgupta S, Li XM, Jansson A, Finnman UB, Matsui T, Rinken A, Arenas E, Agnati LF and Fuxe K (1996) Regulation of dopamine D2 receptor affinity by cholecystokinin octapeptide in fibroblast cells cotransfected with human CCKB and D2L receptor cDNAs. Brain Res Mol Brain Res  36: 292-299[Medline].
  • de Groot RP, Auwerx J, Karperien M, Staels B and Kruijer W (1991) Activation of junB by PKC and PKA signal transduction through a novel cis-acting element. Nucleic Acids Res  19: 775-781[Abstract/Free Full Text].
  • Debry G (1994) Coffee and Health (Debry G ed) pp 1-538, John Libbey, Paris.
  • Deckert J, Nothen MM, Bryant SP, Schuffenhauer S, Schofield PR, Spurr NK and Propping P (1997) Mapping of the human adenosine A2a receptor gene: Relationship to potential schizophrenia loci on chromosome 22q and exclusion from the CATCH 22 region. Hum Genet  99: 326-328[Medline].
  • DeMet E, Stein MK, Tran C, Chicz-DeMet A, Sangdahl C and Nelson J (1989) Caffeine taste test for panic disorder: Adenosine receptor supersensitivity. Psychiatry Res  30: 231-242[Medline].
  • Denaro CP, Brown CR, Jacob P, 3rd and Benowitz NL (1991) Effects of caffeine with repeated dosing. Eur J Clin Pharmacol  40: 273-278[Medline].
  • Deneau G, Yanagita T and Seevers MH (1969) Self-administration of psychoactive substances by the monkey. Psychopharmacologia  16: 30-48.
  • Dews PB (1982) Caffeine. Annu Rev Nutr  2: 323-341[Medline].
  • Diamond I and Gordon AS (1994) The role of adenosine in mediating cellular and molecular responses to ethanol. EXS (Basel)  71: 175-183.[Medline]
  • Di Chiara G (1995) The role of dopamine in drug abuse viewed from the perspective of its role in motivation. Drug Alcohol Depend  38: 95-137[Medline].
  • Dixon AK, Gubitz AK, Sirinathsinghji DJ, Richardson PJ and Freeman TC (1996) Tissue distribution of adenosine receptor mRNAs in the rat. Br J Pharmacol  118: 1461-1468[Medline].
  • Dreisbach RH and Pfeiffer C (1943) Caffeine withdrawal headache. J Lab Clin Med  28: 1212-1219.
  • Dunwiddie TV (1980) Endogenously released adenosine regulates excitability in the in vitro hippocampus. Epilepsia  21: 541-548[Medline].
  • Dunwiddie TV (1985) The physiological role of adenosine in the central nervous system. Int Rev Neurobiol  27: 63-139[Medline].
  • Dunwiddie TV, Hoffer BJ and Fredholm BB (1981) Alkylxanthines elevate hippocampal excitability. Evidence for a role of endogenous adenosine. Naunyn-Schmiedebergs Arch Pharmacol  316: 326-330[Medline].
  • Dux E, Fastbom J, Ungerstedt U, Rudolphi K and Fredholm BB (1990) Protective effect of adenosine and a novel xanthine derivative propentofylline on the cell damage after bilateral carotid occlusion in the gerbil hippocampus. Brain Res  516: 248-256[Medline].
  • Dworkin SI, Vrana SL, Broadbent J and Robinson JH (1993) Comparing the reinforcing effects of nicotine, caffeine, methylphenidate and caffeine. Med Chem Res  2: 593-602.
  • Eaton WW and McLeod J (1984) Consumption of coffee or tea and symptoms of anxiety. Am J Public Health  74: 66-68[Abstract].
  • Edelstein BA, Keaton-Brasted C and Burg MM (1984) Effects of caffeine withdrawal on nocturnal enuresis, insomnia, and behavior restraints. J Consult Clin Psychol  52: 857-862[Medline].
  • Eichler O (1976) Zentrale Wirkung, in Kaffee und Coffein (Eichler O ed) pp 65-102, Springer-Verlag, Berlin, Heidelberg, New York.
  • Ellison CR, Singer MR, Moore LL, Nguyen USDT, Garrahie E and Maror JK (1995) Current caffeine intake in young children: Amounts and sources. J Am Diet Assoc  95: 802-804[Medline].
  • Estler CJ (1982) Caffeine, in Psychoptropic Agents, Part III: Alcohol and Psychotomimetics: Psychotropic Effects of Central Acting Drugs (Hoffmeister F andStille G eds) pp 369-389, Springer-Verlag, Berlin, Heidelberg, New York.
  • Estler C-J (1976) Stoffwechsel Einzelner Organe, in Kaffee und Coffein (Eichler O ed) pp 183-213, Springer-Verlag, Berlin, Heidelberg, New York.
  • Evans SM, Critchfield TS and Griffiths RR (1994) Caffeine reinforcement demonstrated in a majority of caffeine users. Behav Pharmacol  5: 231-238[Medline].
  • Evans SM and Griffiths RR (1991) Dose-related caffeine discrimination in normal volunteers: Individual differences in subjective effects and self-reported cues. Behav Pharmacol  2: 345-356[Medline].
  • Evans SM and Griffiths RR (1992) Caffeine tolerance and choice in humans. Psychopharmacology  108: 51-59[Medline].
  • Falk JL, Zhang J, Chen R and Lau CE (1994) A schedule induction probe technique for evaluating abuse potential: Comparison of ethanol, nicotine and caffeine, and caffeine-midazolam interaction. Behav Pharmacol  5: 513-520[Medline].
  • Fastbom J, Pazos A and Palacios JM (1987) The distribution of adenosine A1 receptors and 5'-nucleotidase in the brain of some commonly used experimental animals. Neuroscience  22: 813-826[Medline].
  • Fennelly M, Galletly DC and Purdie GI (1991) Is caffeine withdrawal the mechanism of postoperative headache? Anesth Analg  72: 449-453[Abstract].
  • Fenu S, Pinna A, Ongini E and Morelli M (1997) Adenosine A2A receptor antagonism potentiates L-DOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats. Eur J Pharmacol  321: 143-147[Medline].
  • Fernström JD and Fernström MH (1984) Effects of caffeine on monoamine neurotransmitters in the central and peripheral nervous system, in Caffeine: Perspectives from Recent Research (Dews PB ed) pp 107-118, Springer-Verlag, Heidelberg.
  • Ferré S, Fredholm BB, Morelli M, Popoli P and Fuxe K (1997) Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci  20: 482-487[Medline].
  • Ferré S, Fuxe K, von Euler G, Johansson B and Fredholm BB (1992) Adenosine-dopamine interactions in the brain. Neuroscience  51: 501-512[Medline].
  • Ferré S, O'Connor WT, Fuxe K and Ungerstedt U (1993) The striopallidal neuron: A main locus for adenosine-dopamine interactions in the brain. J Neurosci  13: 5402-5406[Abstract].
  • Ferré S, O'Connor WT, Svenningsson P, Björklund L, Lindberg J, Tinner B, Strömberg I, Goldstein M, Ögren SO, Ungerstedt U, Fredholm BB and Fuxe K (1996) Dopamine D1 receptor-mediated facilitation of GABAergic neurotransmission in the rat strioentopenduncular pathway and its modulation by adenosine A1 receptor-mediated mechanisms. Eur J Neurosci  8: 1545-1553[Medline].
  • Ferré S, Popoli P, Gimenez-Llort L, Finnman UB, Martinez E, Scotti de Carolis A and Fuxe K (1994) Postsynaptic antagonistic interaction between adenosine A1 and dopamine D1 receptors. Neuroreport  6: 73-76[Medline].
  • Ferré S, Torvinen M, Antoniou K, Irenius E, Civelli O, Arenas E, Fredholm BB and Fuxe K (1998) Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells. J Biol Chem  273: 4718-4724[Abstract/Free Full Text].
  • Ferré S, von Euler G, Johansson B, Fredholm BB and Fuxe K (1991) Stimulation of high-affinity adenosine A2 receptors decreases the affinity of dopamine D2 receptors in rat striatal membranes. Proc Natl Acad Sci USA  88: 7238-7241[Abstract/Free Full Text].
  • Fink JS, Weaver DR, Rivkees SA, Peterfreund RA, Pollack AE, Adler EM and Reppert SM (1992) Molecular cloning of the rat A2 adenosine receptor: Selective co-expression with D2 dopamine receptors in rat striatum. Brain Res Mol Brain Res  14: 186-195[Medline].
  • Finn IB and Holtzman SG (1986) Tolerance to caffeine-induced stimulation of locomotor activity in rats. J Pharmacol Exp Ther  238: 542-546[Abstract/Free Full Text].
  • Finn IB and Holtzman SG (1987) Pharmacologic specificity of tolerance to caffeine-induced stimulation of locomotor activity. Psychopharmacology  93: 428-434[Medline].
  • Foltin RW, Kelly TH and Fischman MW (1995) Effect of amphetamine on human macronutrient intake. Physiol Behav  58: 899-907[Medline].
  • Fox PT and Raichle ME (1986) Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc Natl Acad Sci USA  83: 1140-1144[Abstract/Free Full Text].
  • Fox PT, Raichle ME, Mintun MA and Dence C (1988) Nonoxidative glucose consumption during focal physiologic neural activity. Science  241: 462-464[Abstract/Free Full Text].
  • Franks HM, Hagedorn H, Hensley VR, Hensley WJ and Starmer GA (1975) The effect of caffeine on human performance, alone and in combination with ethanol. Psychopharmacologia  45: 177-181.
  • Fredholm BB (1977) Activation of adenylate cyclase from rat striatum and tuberculum olfactorium by adenosine. Med Biol  55: 262-267[Medline].
  • Fredholm BB (1980) Are methylxanthine effects due to antagonism of endogenous adenosine? Trends Pharmacol Sci  1: 129-132.
  • Fredholm BB (1982) Adenosine actions and adenosine receptors after 1 week treatment with caffeine. Acta Physiol Scand  115: 283-286[Medline].
  • Fredholm BB (1993) Presynaptic regulation of hippocampal acetylcholine release is unaffected by calcium channel blockers and intracellular calcium chelation. Acta Physiol Scand  147: 461-463[Medline].
  • Fredholm BB (1995) Astra Award Lecture. Adenosine, adenosine receptors and the actions of caffeine. Pharmacol Toxicol  76: 93-101[Medline].
  • Fredholm BB, Abbracchio MP, Burnstock G, Daly JW, Harden TK, Jacobson KA, Leff P and Williams M (1994a) Nomenclature and classification of purinoceptors. Pharmacol Rev  46: 143-156[Free Full Text].
  • Fredholm BB and Dunwiddie TV (1988) How does adenosine inhibit transmitter release? Trends Pharmacol Sci  9: 130-134[Medline].
  • Fredholm BB, Fuxe K and Agnati L (1976) Effect of some phosphodiesterase inhibitors on central dopamine mechanisms. Eur J Pharmacol  38: 31-38[Medline].
  • Fredholm BB and Hedqvist P (1980) Modulation of neurotransmission by purine nucleotides and nucleosides. Biochem Pharmacol  29: 1635-1643[Medline].
  • Fredholm BB, Hedqvist P and Vernet L (1978) Effect of theophylline and other drugs on rabbit renal cyclic nucleotide phosphodiesterase, 5'-nucleotidase and adenosine deaminase. Biochem Pharmacol  27: 2845-2850[Medline].
  • Fredholm BB, Herrera-Marschitz M, Jonzon B, Lindström K and Ungerstedt U (1983) On the mechanism by which methylxanthines enhance apomorphine-induced rotation behaviour in the rat. Pharmacol Biochem Behav  19: 535-541[Medline].
  • Fredholm BB and Hu PS (1993) Effect of an intracellular calcium chelator on the regulation of electrically evoked [3H]-noradrenaline release from rat hippocampal slices. Br J Pharmacol  108: 126-131[Medline].
  • Fredholm BB, Johansson B, Lindström K and Wahlström G (1998) Age-dependent changes in adenosine receptors are not modified by life-long intermittent alcohol administration. Brain Res.  791: 177-185[Medline].
  • Fredholm BB and Jonzon B (1988) Adenosine receptors: Agonists and antagonists, in Role of Adenosine in Cerebral Metabolism and Circulation (Stefanovich V andOkayayoz-Baklouti I eds) pp 17-46, VSP BV, Utrecht.
  • Fredholm BB, Jonzon B and Lindgren E (1984) Changes in noradrenaline release and in beta receptor number in rat hippocampus following long-term treatment with theophylline or L-phenylisopropyladenosine. Acta Physiol Scand  122: 55-59[Medline].
  • Fredholm BB and Lerner U (1982) Metabolism of adenosine and 2'-deoxy-adenosine by fetal mouse calvaria in culture. Med Biol  60: 267-271[Medline].
  • Fredholm BB and Lindgren E (1983) Inhibition of soluble 5'-nucleotidase from rat brain by different xanthine derivatives. Biochem Pharmacol  32: 2832-2834[Medline].
  • Fredholm BB, Lindström K and Wallman-Johansson A (1994b) Propentofylline and other adenosine transport inhibitors increase the efflux of adenosine following electrical or metabolic stimulation of rat hippocampal slices. J Neurochem  62: 563-573[Medline].
  • Fredholm BB and Wallman-Johansson A (1996) Effects of ethanol and acetate on adenosine production in rat hippocampal slices. Pharmacol Toxicol  79: 120-123[Medline].
  • Fredholm BB, Zahniser NR, Weiner GR, Proctor WR and Dunwiddie TV (1985) Behavioural sensitivity to PIA in selectively bred mice is related to a number of A1 adenosine receptors but not to cyclic AMP accumulation in brain slices. Eur J Pharmacol  111: 133-136[Medline].
  • Fudin R and Nicastro R (1988) Can caffeine antagonize alcohol-induced performance decrements in humans? Percept Mot Skills  67: 375-391[Medline].
  • Fuhr U, Rost KL, Engelhardt R, Sachs M, Liermann D, Belloc C, Beaune P, Janezic S, Grant D, Meyer UA and Staib AH (1996) Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations. Pharmacogenetics  6: 159-176[Medline].
  • Fuxe K and Ungerstedt U (1974) Action of caffeine and theophyllamine on supersensitive dopamine receptors: Considerable enhancement of receptor response to treatment with DOPA and dopamine receptor agonists. Med Biol  52: 48-54[Medline].
  • Garrett BE and Griffiths RR (1998) Physical dependence increases the relative reinforcing effects of caffeine versus placebo. Psychopharmacology  139: 195-202[Medline].
  • Garrett BE and Holtzman SG (1994a) Caffeine cross-tolerance to selective dopamine D1 and D2 receptor agonists but not to their synergistic interaction. Eur J Pharmacol  262: 65-75[Medline].
  • Garrett BE and Holtzman SG (1994b) D1 and D2 dopamine receptor antagonists block caffeine-induced stimulation of locomotor activity in rats. Pharmacol Biochem Behav  47: 89-94[Medline].
  • Garrett BE and Holtzman SG (1995) Does adenosine receptor blockade mediate caffeine-induced rotational behavior? J Pharmacol Exp Ther  274: 207-214[Abstract/Free Full Text].
  • Gauvin DV, Craido JR, Moore KR and Holloway FA (1990) Potentiation of cocaine's discriminative effects by caffeine: A time-effect analysis. Pharmacol Biochem Behav  36: 195-197[Medline].
  • Gauvin DV, Harland RD, Michaelis RC and Holloway FA (1989) Caffeine-phenylethylamine combinations mimic the cocaine discriminative cue. Life Sci  44: 67-73[Medline].
  • Georgiev V, Johansson B and Fredholm BB (1993) Long-term caffeine treatment leads to a decreased susceptibility to NMDA-induced clonic seizures in mice without changes in adenosine A1 receptor number. Brain Res  612: 271-277[Medline].
  • Gerfen CR (1992) The neostriatal mosaic: Multiple levels of compartmental organization in the basal ganglia. Annu Rev Neurosci  15: 285-320[Medline].
  • Ghelardini C, Galeotti N and Bartolini A (1997) Caffeine induces central cholinergic analgesia. Naunyn-Schmiedebergs Arch Pharmacol  356: 590-595[Medline].
  • Gilbert RM (1976) Caffeine as a drug of abuse, in Research Advances in Alcohol and Drug Problems (Gibbins RJ, Israel Y, Popham RE, Schmidt W andSmart RG eds) pp 49-176, John Wiley & Sons, New York.
  • Gilbert RM (1981) Caffeine, overview and anthology, in Nutrition and Behavior (Miller SA ed) pp 145-166, Franklin Institute Press, Philadelphia.
  • Gilbert RM (1984) Caffeine consumption, in The Methylxanthine Beverages and Foods: Chemistry, Consumption, and Health Effects (Spiller GA ed) pp 185-213, Alan R. Liss, Inc., New York.
  • Gilliland K and Bullock W (1984) Caffeine: A potential drug of abuse. Adv Alcohol Subst Abuse  3: 53-73.
  • Giros B, Jaber M, Jones SR, Wightman RM and Caron MG (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature  379: 606-612[Medline].
  • Goldberg SR and Henningfield JE (1988) Reinforcing effects of nicotine in humans and experimental animals responding under intermittent schedules of i.v. drug injection. Pharmacol Biochem Behav  30: 227-234[Medline].
  • Goldstein A and Kaizer S (1969) Psychotropic effects of caffeine in man: 3. A questionnaire survey of coffee drinking and its effects in a group of housewives. Clin Pharmacol Ther  10: 477-488[Medline].
  • Goldstein A, Kaizer S and Warren R (1965) Psychotropic effects of caffeine in man: II. Alertness, psychomotor coordination, and mood. J Pharmacol Exp Ther  150: 146-151[Abstract/Free Full Text].
  • Goldstein A, Kaizer S and Whitby O (1969) Psychotropic effects of caffeine in man: IV. Quantitative and qualitative differences associated with habituation to coffee. Clin Pharmacol Ther  10: 489-497[Medline].
  • Goldstein A and Wallace ME (1997) Caffeine dependence in schoolchildren? Exp Clin Psychopharmacol  5: 388-392.[Medline]
  • Gonon F and Sundström L (1996) Excitatory effects of dopamine released by impulse flow in the rat nucleus accumbens in vivo. Neuroscience  75: 13-18[Medline].
  • Goodman RR and Snyder SH (1982) Autoradiographic localization of adenosine receptors in rat brain using [3H]cyclohexyladenosine. J Neurosci  2: 1230-1241[Abstract].
  • Graham HN (1984a) Maté, in The Methylxanthine Beverages and Foods: Chemistry, Consumption, and Health Effects (Spiller GA ed) pp 179-183, Alan R. Liss, Inc., New York.
  • Graham HN (1984b) Tea: The plant and its manufacture; chemistry and consumption of the beverage, in The Methylxanthine Beverages and Foods: Chemistry, Consumption, and Health Effects (Spiller GA ed) pp 29-74, Alan R. Liss, Inc., New York.
  • Grant SJ and Redmond DE, Jr (1982) Methylxanthine activation of noradrenergic unit activity and reversal by clonidine. Eur J Pharmacol  85: 105-109[Medline].
  • Graybiel AM, Aosaki T, Flaherty AW and Kimura M (1994) The basal ganglia and adaptive motor control. Science  265: 1826-1831[Abstract/Free Full Text].
  • Greden JF (1974) Anxiety or caffeinism: A diagnostic dilemma. Am J Psychiatry  131: 1089-1092[Abstract/Free Full Text].
  • Green RD, Proudfit HK and Yeung SM (1982) Modulation of striatal dopaminergic function by local injection of 5'-N-ethylcarboxamide adenosine. Science  218: 58-61[Abstract/Free Full Text].
  • Greene RW, Haas HL and Hermann A (1985) Effects of caffeine on hippocampal pyramidal cells in vitro. Br J Pharmacol  85: 163-169[Medline].
  • Greenland S (1993) A meta-analysis of coffee, myocardial infarction, and coronary death. Epidemiology  4: 366-374[Medline].
  • Griebel G, Saffroy-Spittler M, Misslin R, Remmy D, Vogel E and Bourguignon JJ (1991) Comparison of the behavioural effects of an adenosine A1/A2-receptor antagonist, CGS 15943A, and an A1-selective antagonist, DPCPX. Psychopharmacology (Berl)  103: 541-544[Medline].
  • Griffiths RR, Bigelow G and Liebson I (1979) Human drug self-administration: Double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo. J Pharmacol Exp Ther  210: 301-310[Free Full Text].
  • Griffiths RR, Bigelow GE and Liebson IA (1989) Reinforcing effects of caffeine in coffee and capsules. J Exp Anal Behav  52: 127-140[Medline].
  • Griffiths RR, Bigelow GE and Liebson IA (1986a) Human coffee drinking: Reinforcing and physical dependence producing effects of caffeine. J Pharmacol Exp Ther  239: 416-425[Abstract/Free Full Text].
  • Griffiths RR, Bigelow GE, Liebson IA, O'Keeffe M, O'Leary D and Russ N (1986b) Human coffee drinking: Manipulation of concentration and caffeine dose. J Exp Anal Behav  45: 133-148[Medline].
  • Griffiths RR, Evans SM, Heishman SJ, Preston KL, Sannerud CA, Wolf B and Woodson PP (1990) Low-dose caffeine discrimination in humans. J Pharmacol Exp Ther  252: 970-978[Abstract/Free Full Text].
  • Griffiths RR and Mumford GK (1995) Caffeine---A drug of abuse?, in Psychopharmacology: The Fourth Generation of Progress (Bloom FE andKupfer DJ eds) pp 1699-1713, Raven Press, New York.
  • Griffiths RR and Mumford GK (1996) Caffeine reinforcement, discrimination, tolerance and physical dependence in laboratory animals and humans, in Handbook of Experimental Pharmacology (Schuster CR andKuhar MJ eds) pp 315-341, Springer-Verlag, Heidelberg.
  • Griffiths RR and Woodson PP (1988a) Reinforcing effects of caffeine in humans. J Pharmacol Exp Ther  246: 21-29[Abstract/Free Full Text].
  • Griffiths RR and Woodson PP (1988b) Reinforcing properties of caffeine: Studies in humans and laboratory animals. Pharmacol Biochem Behav  29: 419-427[Medline].
  • Griffiths RR and Woodson PP (1988c) Caffeine physical dependence: A review of human and laboratory animal studies. Psychopharmacology  94: 437-451[Medline].
  • Hadfield MG and Milio C (1989) Caffeine and regional brain monoamine utilization in mice. Life Sci  45: 2637-2644[Medline].
  • Hampl KF, Schneider MC, Ruttimann U, Ummenhofer W and Drewe J (1995) Perioperative administration of caffeine tablets for prevention of postoperative headaches. Can J Anaesth  42: 789-792[Abstract/Free Full Text].
  • Harland RD, Gauvin DV, Michaelis RC, Carney JM, Seale TW and Holloway FA (1989) Behavioral interaction between cocaine and caffeine: A drug discrimination analysis in rats. Pharmacol Biochem Behav  32: 1017-1023[Medline].
  • Hart P, Farrell GC, Cooksley WG and Powell LW (1976) Enhanced drug metabolism in cigarette smokers. Br Med J  2: 147-149[Medline].
  • Harvey J and Lacey MG (1997) A postsynaptic interaction between dopamine D1 and NMDA receptors promotes presynaptic inhibition in the rat nucleus accumbens via adenosine release. J Neurosci  17: 5271-5280[Abstract/Free Full Text].
  • Hasenfratz M and Bättig K (1992) Action profiles of smoking and caffeine: Stroop effect, EEG, and peripheral physiology. Pharmacol Biochem Behav  42: 155-161[Medline].
  • Hasenfratz M, Bunge A, Dal Pra G and Bättig K (1993) Antagonistic effects of caffeine and alcohol on mental performance parameters. Pharmacol Biochem Behav  46: 463-465[Medline].
  • Hasenfratz M, Buzzini P, Cheda P and Bättig K (1994) Temporal relationships of the effects of caffeine and alcohol on rapid information processing. Pharmacopsychoecologia  7: 87-96.
  • Hasenfratz M, Jaquet F, Aeschbach D and Bättig K (1991) Interactions of smoking and lunch with the effects of caffeine on cardiovascular functions and information processing. Hum Psychopharmacol  6: 277-284.
  • Hauber W and Koch M (1997) Adenosine A2a receptors in the nucleus accumbens modulate prepulse inhibition of the startle response. Neuroreport  8: 1515-1518[Medline].
  • Hauber W and Münkle M (1997) Motor depressant effects mediated by dopamine D2 and adenosine A2A receptors in the nucleus accumbens and the caudate-putamen. Eur J Pharmacol  323: 127-131[Medline].
  • Hedqvist P and Fredholm BB (1976) Effects of adenosine on adrenergic neurotransmission; prejunctional inhibition and postjunctional enhancement. Naunyn-Schmiedebergs Arch Pharmacol  293: 217-223[Medline].
  • Hedqvist P, Fredholm BB and Ölundh S (1978) Antagonistic effects of theophylline and adenosine on adrenergic neuroeffector transmission in the rabbit kidney. Circ Res  43: 592-598[Abstract].
  • Heimer L, Alheid GF and Zaborszky L (1985) Basal ganglia, in The Rat Nervous System (Paxinos G ed) pp 37-86, Academic Press, Marrickville, NSW, Australia.
  • Heishman SJ and Henningfield JE (1994) Is caffeine a drug of dependence? Criteria and comparisons. Pharmacopsychoecologia  7: 127-136.
  • Henry DJ and White FJ (1995) The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons. J Neurosci  15: 6287-6299[Abstract].
  • Heppner CC, Kemble ED and Cox WM (1986) Effects of food deprivation on caffeine consumption in male and female rats. Pharmacol Biochem Behav  24: 1555-1559[Medline].
  • Herrera-Marschitz M, Casas M and Ungerstedt U (1988) Caffeine produces contralateral rotation in rats with unilateral dopamine denervation: Comparisons with apomorphine-induced responses. Psychopharmacology  94: 38-45[Medline].
  • Hicks RA, Hicks GJ, Reyes JR and Cheers Y (1983) Daily caffeine use and the sleep of college students. Bull Psychon Soc  21: 24-25.
  • Hirsh K (1984) Central nervous system pharmacology of the methylxanthines, in The Methylxanthine Beverages and Foods: Chemistry, Composition and Health Effects (Spiller GA ed) pp 235-301, Alan R. Liss, New York.
  • Höfer I and Bättig K (1993) Coffee consumption, blood pressure tonus and reactivity to physical challenge in 338 women. Pharmacol Biochem Behav  44: 573-576[Medline].
  • Höfer I and Bättig K (1994a) Cardiovascular, behavioral, and subjective effects of caffeine under field conditions. Pharmacol Biochem Behav  48: 899-908[Medline].
  • Höfer I and Bättig K (1994b) Psychophysiological effects of switching to caffeine tablets or decaffeinated coffee under field conditions. Pharmacopsychoecologia  7: 169-177.
  • Hoffmeister F and Wuttke W (1973) Self-administration of acetylsalicylic acid and combinations with codeine and caffeine in rhesus monkeys. J Pharmacol Exp Ther  186: 266-275[Abstract/Free Full Text].
  • Holloway WR, Jr and Thor DH (1983) Caffeine and social investigation in the adult male rat. Neurobehav Toxicol Teratol  5: 119-125[Medline].
  • Holloway FA, Modrow HE and Michaelis RC (1985) Methylxanthine discrimination in the rat: Possible benzodiazepine and adenosine mechanisms. Pharmacol Biochem Behav  22: 815-824[Medline].
  • Holtzman SG (1983) Complete, reversible, drug-specific tolerance to stimulation of locomotor activity by caffeine. Life Sci  33: 779-787[Medline].
  • Holtzman SG (1986) Discriminative stimulus properties of caffeine in the rat: Noradrenergic mediation. J Pharmacol Exp Ther  239: 706-714[Abstract/Free Full Text].
  • Holtzman SG (1990) Caffeine as a model drug of abuse. Trends Pharmacol Sci  11: 355-356[Medline].
  • Holtzman SG (1996) Discriminative effects of CGS 15943, a competitive adenosine receptor antagonist, in monkeys: Comparison to methylxanthines. J Pharmacol Exp Ther  277: 739-746[Abstract/Free Full Text].
  • Holtzman SG and Finn IB (1988) Tolerance to behavioral effects of caffeine in rats. Pharmacol Biochem Behav  29: 411-418[Medline].
  • Holtzman SG, Mante S and Minneman KP (1991) Role of adenosine receptors in caffeine tolerance. J Pharmacol Exp Ther  256: 62-68[Abstract/Free Full Text].
  • Horger BA, Wellman PJ, Morien A, Davies BT and Schenk S (1991) Caffeine exposure sensitizes rats to the reinforcing effects of cocaine. Neuroreport  2: 53-56[Medline].
  • Horne JA and Reyner LA (1996) Counteracting driver sleepiness: Effects of napping, caffeine, and placebo. Psychophysiology  33: 306-309[Medline].
  • Howell LL, Coffin VL and Spealman RD (1997) Behavioral and physiological effects of xanthines in nonhuman primates. Psychopharmacology  129: 1-14[Medline].
  • Hughes JR, Hunt WK, Higgins ST, Bickel WK, Fenwick JW and Pepper SL (1992a) Effect of dose on the ability of caffeine to serve as a reinforcer in humans. Behav Pharmacol  3: 221-218.
  • Hughes JR and Oliveto AH (1997) A systematic survey of caffeine intake in Vermont. Exp Clin Psychopharmacol  5: 393-398.[Medline]
  • Hughes JR, Oliveto AH, Bickel WK, Higgins ST and Badger GJ (1993) Caffeine self-administration and withdrawal: Incidence, individual differences and interrelationships. Drug Alcohol Depend  32: 239-246[Medline].
  • Hughes JR, Oliveto AH, Helzer JE, Higgins ST and Bickel WK (1992b) Should caffeine abuse, dependence, or withdrawal be added to DSM-IV and ICD-10? Am J Psychiatry  149: 33-40[Abstract].
  • Hughes JR, Oliveto AH, Liguori A, Carpenter J and Howard T (1998) Endorsement of DSM-IV dependence criteria among caffeine users. Drug Alcohol Depend  52: 99-107[Medline].
  • Hughes RN (1996) Drugs which induce anxiety: Caffeine. New Zeal J Psychol  25: 36-42.
  • Huston JP, Haas HL, Boix F, Pfister M, Decking U, Schrader J and Schwarting RK (1996) Extracellular adenosine levels in neostriatum and hippocampus during rest and activity periods of rats. Neuroscience  73: 99-107[Medline].
  • Hyman SE (1996) Addiction to cocaine and amphetamine. Neuron  16: 901-904[Medline].
  • IARC Working Group (1991) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans: Coffee, Tea, Maté, Methylxanthines and Methylglyoxal. International Agency for Research on Cancer, Lyon.
  • Ikeda GJ, Sapienza PP, McGinnis ML, Bragg LE, Walsh JJ and Collins TF (1982) Blood levels of caffeine and results of fetal examination after oral administration of caffeine to pregnant rats. J Appl Toxicol  2: 307-314[Medline].
  • Ikemoto S, Glazier BS, Murphy JM and McBride WJ (1997) Role of dopamine D1 and D2 receptors in the nucleus accumbens in mediating reward. J Neurosci  17: 8580-8587[Abstract/Free Full Text].
  • Istvan J and Matarazzo JD (1984) Tobacco, alcohol, and caffeine use: A review of their interrelationships. Psychol Bull  95: 301-326[Medline].
  • Jaber M, Robinson SW, Missale C and Caron MG (1996) Dopamine receptors and brain function. Neuropharmacology  35: 1503-1519[Medline].
  • Jacobsen BK and Hansen V (1988) Caffeine and health. Br Med J Clin Res  296: 291.
  • Jacobson KA, von Lubitz DK, Daly JW and Fredholm BB (1996) Adenosine receptor ligands: Differences with acute versus chronic treatment. Trends Pharmacol Sci  17: 108-113[Medline].
  • James JE (1991) Caffeine and Health pp 1-432, Academic Press, London.
  • James JE (1994) Does caffeine enhance or merely restore degraded psychomotor performance? Neuropsychobiology  30: 124-125[Medline].
  • James JE (1995) Caffeine and psychomotor performance revisited. Neuropsychobiology  31: 202-203[Medline].
  • Jarvis MF and Williams M (1989) Direct autoradiographic localization of adenosine A2 receptors in the rat brain using the A2-selective agonist, [3H]CGS 21680. Eur J Pharmacol  168: 243-246[Medline].
  • Jin S and Fredholm BB (1997) Adenosine A2A receptor stimulation increases release of acetylcholine from rat hippocampus but not striatum, and does not affect catecholamine release. Naunyn-Schmiedebergs Arch Pharmacol  355: 48-56[Medline].
  • Jin S, Johansson B and Fredholm BB (1993) Effects of adenosine A1 and A2 receptor activation on electrically evoked dopamine and acetylcholine release from rat striatal slices. J Pharmacol Exp Ther  267: 801-808[Abstract/Free Full Text].
  • Joeres R, Klinker H, Heusler H, Epping J, Zilly W and Richter E (1988) Influence of smoking on caffeine elimination in healthy volunteers and in patients with alcoholic liver cirrhosis. Hepatology  8: 575-579[Medline].
  • Johansson B, Ahlberg S, van der Ploeg I, Brené S, Lindefors N, Persson H and Fredholm BB (1993a) Effect of long term caffeine treatment on A1 and A2 adenosine receptor binding and on mRNA levels in rat brain. Naunyn-Schmiedebergs Arch Pharmacol  347: 407-414[Medline].
  • Johansson B and Fredholm BB (1995) Further characterization of the binding of the adenosine receptor agonist [3H]CGS 21680 to rat brain using autoradiography. Neuropharmacology  34: 393-403[Medline].
  • Johansson B, Georgiev V, Kuosmanen T and Fredholm BB (1996a) Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding. Eur J Neurosci  8: 2447-2458[Medline].
  • Johansson B, Georgiev V, Parkinson FE and Fredholm BB (1993b) The binding of the adenosine A2 receptor selective agonist [3H]CGS 21680 to rat cortex differs from its binding to rat striatum. Eur J Pharmacol  247: 103-110[Medline].
  • Johansson B, Lindström K and Fredholm BB (1994) Differences in the regional and cellular localization of c-fos messenger RNA induced by amphetamine, cocaine and caffeine in the rat. Neuroscience  59: 837-849[Medline].
  • Johansson L, Drevon CA and Aa Bjorneboe GE (1996b) The Norwegian diet during the last hundred years in relation to coronary heart disease. Eur J Clin Nutr  50: 277-283[Medline].
  • Johnson SW and North RA (1992) Opioids excite dopamine neurons by hyperpolarization of local interneurons. J Neurosci  12: 483-488[Abstract].
  • Johnson SW, Seutin V and North RA (1992) Burst firing in dopamine neurons induced by N-methyl-D-aspartate: Role of electrogenic sodium pump. Science  258: 665-667[Abstract/Free Full Text].
  • Jonzon B and Fredholm BB (1985) Release of purines, noradrenaline and GABA from rat hippocampal slices by field stimulation. J Neurochem  44: 217-224[Medline].
  • Josselyn SA and Beninger RJ (1991) Behavioral effects of intrastriatal caffeine mediated by adenosinergic modulation of dopamine. Pharmacol Biochem Behav  39: 97-103[Medline].
  • Jouvet M, Benoit O, Marsallon A and Courjon J (1957) Action de la caféine sur l'activité électrique cérébrale. C R Soc Biol  151: 1542-1545.
  • Kaplan GB, Greenblatt DJ, Ehrenberg BL, Goddard JE, Cotreau MM, Harmatz JS and Shader RI (1997) Dose-dependent pharmacokinetics and psychomotor effects of caffeine in humans. J Clin Pharmacol  37: 693-703[Abstract].
  • Kaplan GB, Greenblatt DJ, Kent MA and Cotreau-Bibbo MM (1993) Caffeine treatment and withdrawal in mice: Relationships between dosage, concentrations, locomotor activity and A1 adenosine receptor binding. J Pharmacol Exp Ther  266: 1563-1572[Abstract/Free Full Text].
  • Kaplan GB, Tai NT, Greenblatt DJ and Shader RI (1990) Caffeine-induced behavioural stimulation is dose- and concentration-dependent. Br J Pharmacol  100: 435-440[Medline].
  • Karler R, Calder LD, Chaudhry IA and Turkanis SA (1989) Blockade of "reverse tolerance" to cocaine and amphetamine by MK-801. Life Sci  45: 599-606[Medline].
  • Katsura M, Hashimoto T and Kuriyama K (1991) Effect of 1,3-di-n-butyl-7-(2-oxopropyl)-xanthine (denbufylline) on metabolism and function of cerebral cholinergic neurons. Jpn J Pharmacol  55: 233-240[Medline].
  • Kawachi I, Colditz GA and Stone CB (1994) Does coffee drinking increase the risk of coronary heart disease? Results from a meta-analysis. Br Heart J  72: 269-275[Abstract].
  • Kawachi I, Willett WC, Colditz GA, Stampfer MJ and Speizer FE (1996) A prospective study of coffee drinking and suicide in women. Arch Intern Med  156: 521-525[Abstract].
  • Kenemans JL and Lorist MM (1995) Caffeine and selective visual processing. Pharmacol Biochem Behav  52: 461-471[Medline].
  • Kerr JS, Sherwood N and Hindmarch I (1991) Separate and combined effects of the social drugs on psychomotor performance. Psychopharmacology  104: 113-119[Medline].
  • Khanna NN, Bada HS and Somani SM (1980) Use of salivary concentrations in the prediction of serum caffeine and theophylline concentrations in premature infants. J Pediatr  96: 494-499[Medline].
  • Khanna NN and Somani SM (1984) Maternal coffee drinking and unusually high concentrations of caffeine in the newborn. J Toxicol Clin Toxicol  22: 473-483[Medline].
  • Kilty JE, Lorang D and Amara SG (1991) Cloning and expression of a cocaine-sensitive rat dopamine transporter. Science  254: 578-579[Abstract/Free Full Text].
  • Kimmel CA, Kimmel GL, White CG, Grafton TF, Young JF and Nelson CJ (1984) Blood flow changes and conceptual development in pregnant rats in response to caffeine. Fundam Appl Toxicol  4: 240-247[Medline].
  • Kirk IP and Richardson PJ (1994) Adenosine A2a receptor-mediated modulation of striatal [3H]GABA and [3H]acetylcholine release. J Neurochem  62: 960-966[Medline].
  • Knutti R, Rothweiler H and Schlatter C (1981) Effect of pregnancy on the pharmacokinetics of caffeine. Eur J Clin Pharmacol  21: 121-126[Medline].
  • Koch M and Hauber W (1998) Regulation of sensorimotor gating by interactions of dopamine and adenosine in the rat. Behav Pharmacology  9: 23-29[Medline].
  • Koelega HS (1993) Stimulant drugs and vigilance performance: A review. Psychopharmacology  111: 1-16[Medline].
  • Konradi C, Cole RL, Heckers S and Hyman SE (1994) Amphetamine regulates gene expression in rat striatum via transcription factor CREB. J Neurosci  14: 5623-5634[Abstract].
  • Koob GF (1992) Drugs of abuse: Anatomy, pharmacology and function of reward pathways. Trends Pharmacol Sci  13: 177-184[Medline].
  • Koob GF (1996) Drug addiction: The yin and yang of hedonic homeostasis. Neuron  16: 893-896[Medline].
  • Kozlowski LT (1976) Effect of caffeine on coffee drinking. Nature  264: 354-355[Medline].
  • Kull B, Arslan G, Nilsson C, Owman C, Lorenzen A, Schwabe U and Fredholm BB (1999) Differences in the order of potency for agonists at human and rat adenosine A2A receptors. Biochem Pharmacol  57: 65-75[Medline].
  • Kurokawa M, Kirk IP, Kirkpatrick KA, Kase H and Richardson PJ (1994) Inhibition by KF17837 of adenosine A2A receptor-mediated modulation of striatal GABA and ACh release. Br J Pharmacol  113: 43-48[Medline].
  • Kuznicki JT and Turner LS (1986) The effects of caffeine on caffeine users and non-users. Physiol Behav  37: 397-408[Medline].
  • La Vecchia C (1993) Coffee and cancer epidemiology, in Caffeine, Coffee and Health (Garattini S ed) pp 379-398, Raven Press, New York.
  • Lachance MP, Marlowe C and Waddell WJ (1983) Autoradiographic disposition of [1-methyl-14C]- and [2-14C]caffeine in mice. Toxicol Appl Pharmacol  71: 237-241[Medline].
  • Lack LC, Müller W and Turner D (1988) A survey of sleeping difficulties in an Australian population. Community Health Studies  12: 200-207[Medline].
  • Landolt HP, Dijk DJ, Gaus SE and Borbely AA (1995a) Caffeine reduces low-frequency delta activity in the human sleep EEG. Neuropsychopharmacology  12: 229-238[Medline].
  • Landolt HP, Werth E, Borbely AA and Dijk DJ (1995b) Caffeine intake (200 mg) in the morning affects human sleep and EEG power spectra at night. Brain Res  675: 67-74[Medline].
  • Lane JD (1996) Association of coffee drinking with cigarette smoking in the natural environment. Exp Clin Psychopharmacol  4: 409-412.
  • Lane JD (1997) Effects of brief caffeinated-beverage deprivation on mood, symptoms, and psychomotor performance. Pharmacol Biochem Behav  58: 203-208[Medline].
  • Lau CE and Falk JL (1994) Tolerance to oral and IP caffeine: Locomotor activity and pharmacokinetics. Pharmacol Biochem Behav  48: 337-344[Medline].
  • Lau CE and Falk JL (1995) Dose-dependent surmountability of locomotor activity in caffeine tolerance. Pharmacol Biochem Behav  52: 139-143[Medline].
  • Le Guennec JC and Billon B (1987) Delay in caffeine elimination in breast-fed infants. Pediatrics  79: 264-268[Medline].
  • Le Moine C, Svenningsson P, Fredholm BB and Bloch B (1997) Dopamine-adenosine interactions in the striatum and the globus pallidus: Inhibition of striatopallidal neurons through either D2 or A2A receptors enhances D1 receptor-mediated effects on c-fos expression. J Neurosci  17: 8038-8048[Abstract/Free Full Text].
  • Ledent C, Vaugeois JM, Schiffmann SN, Pedrazzini T, Elyacoubi M, Vanderhaeghen JJ, Costentin J, Heath JK, Vassart G and Parmentier M (1997) Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2A receptor. Nature  388: 674-678[Medline].
  • Lee MA, Cameron OG and Greden JF (1985) Anxiety and caffeine consumption in people with anxiety disorders. Psychiatry Res  15: 211-217[Medline].
  • Levy M and Zylber-Katz E (1983) Caffeine metabolism and coffee-attributed sleep disturbances. Clin Pharmacol Ther  33: 770-775[Medline].
  • Lieberman HR, Wurtman RJ, Emde GG and Coviella IL (1987) The effects of caffeine and aspirin on mood and performance. J Clin Psychopharmacol  7: 315-320[Medline].
  • Liguori A, Hughes JR, Goldberg K and Callas P (1997) Subjective effects of oral caffeine in formerly cocaine-dependent humans. Drug Alcohol Depend  49: 17-24[Medline].
  • Lindström K, Ongini E and Fredholm BB (1996) 2-Chloro-NECA and SCH 58261 discriminate between two different binding sites for CGS 21680. Naunyn-Schmiedebergs Arch Pharmacol  354: 539-541[Medline].
  • Litovitz TL, Martin TG and Schmitz B (1987) 1986 annual report of the American Association of Poison Control Centers National Data Collection System. Am J Emerg Med  5: 405-445[Medline].
  • Lloyd HG and Fredholm BB (1995) Involvement of adenosine deaminase and adenosine kinase in regulating extracellular adenosine concentration in rat hippocampal slices. Neurochem Int  26: 387-395[Medline].
  • Lloyd HG, Lindström K and Fredholm BB (1993) Intracellular formation and release of adenosine from rat hippocampal slices evoked by electrical stimulation or energy depletion. Neurochem Int  23: 173-185[Medline].
  • Lopez F, Miller LG, Greenblatt DJ, Kaplan GB and Shader RI (1989) Interaction of caffeine with the GABAA receptor complex: Alterations in receptor function but not ligand binding. Eur J Pharmacol (Mol Pharmacol Sect)  172: 453-459[Medline].
  • Lorist MM, Snel J and Kok A (1994) Influence of caffeine on information processing stages in well rested and fatigued subjects. Psychopharmacology  113: 411-421[Medline].
  • Mahan LC, McVittie LD, Smyk-Randall EM, Nakata H, Monsma FJ, Jr, Gerfen CR and Sibley DR (1991) Cloning and expression of an A1 adenosine receptor from rat brain. Mol Pharmacol  40: 1-7[Abstract].
  • Maldonado R, Saiardi A, Valverde O, Samad TA, Roques BP and Borrelli E (1997) Absence of opiate rewarding effects in mice lacking dopamine D2 receptors. Nature  388: 586-589[Medline].
  • Manber R, Bootzin RR, Acebo C and Carskadon MA (1996) The effects of regularizing sleep-wake schedules on daytime sleepiness. Sleep  19: 432-441[Medline].
  • Marks V and Kelly JF (1973) Absorption of caffeine from tea, coffee, and coca cola. Lancet  1: 827[Medline].
  • Mathew RJ and Wilson WH (1985) Caffeine consumption, withdrawal and cerebral blood flow. Headache  25: 305-309[Medline].
  • Mayfield RD, Suzuki F and Zahniser NR (1993) Adenosine A2a receptor modulation of electrically evoked endogenous GABA release from slices of rat globus pallidus. J Neurochem  60: 2334-2337[Medline].
  • McCall AL, Millington WR and Wurtman RJ (1982) Blood-brain barrier transport of caffeine: Dose-related restriction of adenine transport. Life Sci  31: 2709-2715[Medline].
  • McGowan JD, Altman RE and Kanto WP, Jr (1988) Neonatal withdrawal symptoms after chronic maternal ingestion of caffeine. South Med J  81: 1092-1094[Medline].
  • McPherson PS, Kim YK, Valdivia H, Knudson CM, Takekura H, Franzini-Armstrong C, Coronado R and Campbell KP (1991) The brain ryanodine receptor: A caffeine-sensitive calcium release channel. Neuron  7: 17-25[Medline].
  • Mellstrom B, Achaval M, Montero D, Naranjo JR and Sassone-Corsi P (1991) Differential expression of the jun family members in rat brain. Oncogene  6: 1959-1964[Medline].
  • Meng ZH, Anwer J and Dar MS (1997) The striatal adenosinergic modulation of ethanol-induced motor incoordination in rats: Possible role of chloride flux. Brain Res  776: 235-245[Medline].
  • Meng ZH and Dar MS (1995) Possible role of striatal adenosine in the modulation of acute ethanol-induced motor incoordination in rats. Alcohol Clin Exp Res  19: 892-901[Medline].
  • Merchant KM and Dorsa DM (1993) Differential induction of neurotensin and c-fos gene expression by typical versus atypical antipsychotics. Proc Natl Acad Sci USA  90: 3447-3451[Abstract/Free Full Text].
  • Migliardi JR, Armellino JJ, Friedman M, Gillings DB and Beaver WT (1994) Caffeine as an analgesic adjuvant in tension headache. Clin Pharmacol Ther  56: 576-586[Medline].
  • Mikkelsen EJ (1978) Caffeine and schizophrenia. J Clin Psychiatry  39: 732-736[Medline].
  • Milbrandt J (1987) A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor. Science  238: 797-799[Abstract/Free Full Text].
  • Milbrandt J (1988) Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene. Neuron  1: 183-188[Medline].
  • Miners JO and Birkett DJ (1996) The use of caffeine as a metabolic probe for human drug metabolizing enzymes. Gen Pharmacol  27: 245-249[Medline].
  • Mirenowicz J and Schultz W (1994) Importance of unpredictability for reward responses in primate dopamine neurons. J Neurophysiol  72: 1024-1027[Abstract/Free Full Text].
  • Mitchell SH, de Wit H and Zacny JP (1995) Caffeine withdrawal symptoms and self-administration following caffeine deprivation. Pharmacol Biochem Behav  51: 941-945[Medline].
  • Modrow HE and Holloway FA (1985) Drug discrimination and cross generalization between two methylxanthines. Pharmacol Biochem Behav  23: 425-429[Medline].
  • Modrow HE, Holloway FA and Carney JM (1981) Caffeine discrimination in the rat. Pharmacol Biochem Behav  14: 683-688[Medline].
  • Mogul DJ, Adams ME and Fox AP (1993) Differential activation of adenosine receptors decreases N-type but potentiates P-type Ca2+ current in hippocampal CA3 neurons. Neuron  10: 327-334[Medline].
  • Mohr U, Emura M and Riebe-Imre M (1993) Experimental studies on carcinogenicity and mutagenicity of caffeine, in Caffeine, Coffee and Health (Garattini S ed) pp 359-378, Raven Press, New York.
  • Moratalla R, Robertson HA and Graybiel AM (1992) Dynamic regulation of NGFI-A (zif268, egr1) gene expression in the striatum. J Neurosci  12: 2609-2622[Abstract].
  • Morelli M, Fenu S, Carta A and Di Chiara G (1996) Effect of MK 801 on priming of D1-dependent contralateral turning and its relationship to c-fos expression in the rat caudate-putamen. Behav Brain Res  79: 93-100[Medline].
  • Morelli M, Fenu S, Pinna A and Di Chiara G (1994) Adenosine A2 receptors interact negatively with dopamine D1 and D2 receptors in unilaterally 6-hydroxydopamine-lesioned rats. Eur J Pharmacol  251: 21-25[Medline].
  • Morgan KJ, Stults VJ and Zabik ME (1982) Amount and dietary sources of caffeine and saccharin intake by individuals ages 5 to 18 years. Regul Toxicol Pharmacol  2: 296-307[Medline].
  • Morgan ME and Vestal RE (1989) Methylxanthine effects on caudate dopamine release as measured by in vivo electrochemistry. Life Sci  45: 2025-2039[Medline].
  • Muehlbach MJ and Walsh JK (1995) The effects of caffeine on simulated night-shift work and subsequent daytime sleep. Sleep  18: 22-29[Medline].
  • Mumford GK and Holtzman SG (1991) Qualitative differences in the discriminative stimulus effects of low and high doses of caffeine in the rat. J Pharmacol Exp Ther  258: 857-865[Abstract/Free Full Text].
  • Mumford GK, Neill DB and Holtzman SG (1988) Caffeine elevates reinforcement threshold for electrical brain stimulation: Tolerance and withdrawal changes. Brain Res  459: 163-167[Medline].
  • Murphy TL, McIvor C, Yap A, Cooksley WG, Halliday JW and Powell LW (1988) The effect of smoking on caffeine elimination: Implications for its use as a semiquantitative test of liver function. Clin Exp Pharmacol Physiol  15: 9-13[Medline].
  • Murray TF, Blaker WD, Cheney DL and Costa E (1982) Inhibition of acetylcholine turnover rate in rat hippocampus and cortex by intraventricular injection of adenosine analogs. J Pharmacol Exp Ther  222: 550-554[Abstract/Free Full Text].
  • Myers DE, Shaikh Z and Zullo TG (1997) Hypoalgesic effect of caffeine in experimental ischemic muscle contraction pain. Headache  37: 654-658[Medline].
  • Myers MG and Basinski A (1992) Coffee and coronary heart disease. Arch Intern Med  152: 1767-1772[Abstract].
  • Nehlig A, Daval JL, Boyet S and Vert P (1986) Comparative effects of acute and chronic administration of caffeine on local cerebral glucose utilization in the conscious rat. Eur J Pharmacol  129: 93-103[Medline].
  • Nehlig A, Daval JL and Debry G (1992) Caffeine and the central nervous system: Mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Rev  17: 139-170[Medline].
  • Nehlig A and Debry G (1994) Effects of coffee on the central nervous system, in Coffee and Health (Debry G ed) pp 157-249, John Libbey, Montrouge.
  • Nehlig A, Lucignani G, Kadekaro M, Porrino LJ and Sokoloff L (1984) Effects of acute administration of caffeine on local cerebral glucose utilization in the rat. Eur J Pharmacol  101: 91-100[Medline].
  • Nehlig A, Pereira de Vasconcelos A, Dumont I and Boyet S (1990) Effects of caffeine, L-phenylisopropyladenosine and their combination on local cerebral blood flow in the rat. Eur J Pharmacol  179: 271-280[Medline].
  • Nestler EJ, Terwilliger RZ, Walker JR, Sevarino KA and Duman RS (1990) Chronic cocaine treatment decreases levels of the G protein subunits Gi alpha and Go alpha in discrete regions of rat brain. J Neurochem  55: 1079-1082[Medline].
  • Nguyen TV, Kosofsky BE, Birnbaum R, Cohen BM and Hyman SE (1992) Differential expression of c-fos and zif268 in rat striatum after haloperidol, clozapine, and amphetamine. Proc Natl Acad Sci USA  89: 4270-4274[Abstract/Free Full Text].
  • Nikodijeviç O, Jacobson KA and Daly JW (1993) Locomotor activity in mice during chronic treatment with caffeine and withdrawal. Pharmacol Biochem Behav  44: 199-216[Medline].
  • Nikolajsen L, Larsen KM and Kierkegaard O (1994) Effect of previous frequency of headache, duration of fasting and caffeine abstinence on perioperative headache. Br J Anaesth  72: 295-297[Abstract/Free Full Text].
  • Nygård O, Refsum H, Ueland PM and Vollset SE (1998) Major lifestyle determinants of plasma total homocysteine distribution: The Hordaland Homocysteine Study. Am J Clin Nutr  67: 263-270[Abstract].
  • O'Brien CP (1995) Drug addiction and drug abuse, in Goodman and Gilman's The Pharmacological Basis of Therapeutics (Hardman JG, Limbird LE, Molinoff PB, Ruddon RW andGilman AG eds) pp 557-577, McGraw Hill, New York.
  • O'Connor SD, Stojanovic M and Radulovacki M (1991) The effect of soluflazine on sleep in rats. Neuropharmacology  30: 671-674[Medline].
  • Ohno M and Watanabe S (1996) Working memory failure by stimulation of hippocampal adenosine A1 receptors in rats. Neuroreport  7: 3013-3016[Medline].
  • Okada M, Kiryu K, Kawata Y, Mizuno K, Wada K, Tasaki H and Kaneko S (1997) Determination of the effects of caffeine and carbamazepine on striatal dopamine release by in vivo microdialysis. Eur J Pharmacol  321: 181-188[Medline].
  • Olds J (1956) Pleasure centers in the brain. Sci Am  195: 105-116.
  • Olds J and Milner PM (1954) Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. J Comp Physiol Psychol  47: 419-427[Medline].
  • Olekalns N and Bardsley P (1995) Caffeine dependence syndrome. JAMA  273: 1417-1418[Medline].
  • Olekalns N and Bardsley P (1996) Rational addiction to caffeine: An analysis of coffee consumption. J Polit Econ  104: 1100-1104.
  • Oliveto AH, Bickel WK, Hughes JR, Terry SY, Higgins ST and Badger GJ (1993) Pharmacological specificity of the caffeine discriminative stimulus in humans: Effects of theophylline, methylphenidate and buspirone. Behav Pharmacol  4: 237-246[Medline].
  • Ongini E and Fredholm BB (1996) Pharmacology of adenosine A2A receptors. Trends Pharmacol Sci  17: 364-372[Medline].
  • Orzi F, Morelli M, Fieschi C and Pontieri FE (1993) Metabolic mapping of the pharmacological and toxicological effects of dopaminergic drugs in experimental animals. Cerebrovasc Brain Metab Rev  5: 95-121[Medline].
  • Paire M, Van Lieferinhen P, Desvignes V, Dubray C, Raynaud EJ and Lavarenne J (1988) Cinétique de la caféine au cours des premiers mois de la vie et implications pratiques. Sem Hôp Paris  64: 1813-1817.
  • Pantelios G, Lack L and James JE (1989) Caffeine consumption and sleep. Sleep  18: 65.
  • Parkinson FE and Fredholm BB (1990) Autoradiographic evidence for G-protein coupled A2-receptors in rat neostriatum using [3H]-CGS 21680 as a ligand. Naunyn-Schmiedebergs Arch Pharmacol  342: 85-89[Medline].
  • Parsons WD and Neims AH (1981) Prolonged half-life of caffeine in healthy term newborn infants. J Pediatr  98: 640-641[Medline].
  • Patwardhan RV, Desmond PV, Johnson RF and Schenker S (1980) Impaired elimination of caffeine by oral contraceptive steroids. J Lab Clin Med  95: 603-608[Medline].
  • Paul ML, Graybiel AM, David JC and Robertson HA (1992) D1-like and D2-like dopamine receptors synergistically activate rotation and c-fos expression in the dopamine-depleted striatum in a rat model of Parkinson's disease. J Neurosci  12: 3729-3742[Abstract].
  • Pearlman SA, Duran C, Wood MA, Maisels MJ and Berlin CM, Jr (1989) Caffeine pharmacokinetics in preterm infants older than 2 weeks. Dev Pharmacol Ther  12: 65-69[Medline].
  • Penetar D, McCann U, Thorne D, Kamimori G, Galinski C, Sing H, Thomas M and Belenky G (1993) Caffeine reversal of sleep deprivation effects on alertness and mood. Psychopharmacology  112: 359-365[Medline].
  • Peris J, Boyson SJ, Cass WA, Curella P, Dwoskin LP, Larson G, Lin LH, Yasuda RP and Zahniser NR (1990) Persistence of neurochemical changes in dopamine systems after repeated cocaine administration. J Pharmacol Exp Ther  253: 38-44[Abstract/Free Full Text].
  • Perkins KA, Sexton JE, Epstein LH, DiMarco A, Fonte C, Stiller RL, Scierka A and Jacob RG (1994) Acute thermogenic effects of nicotine combined with caffeine during light physical activity in male and female smokers. Am J Clin Nutr  60: 312-319[Abstract/Free Full Text].
  • Phillips-Bute BG and Lane JD (1998) Caffeine withdrawal symptoms following brief caffeine deprivation. Physiol Behav  63: 35-39.
  • Phillis JW and Edstrom JP (1976) Effects of adenosine analogs on rat cerebral cortical neurons. Life Sci  19: 1041-1053[Medline].
  • Phillis JW, Jiang ZG, Chelack BJ and Wu PH (1980) The effect of morphine on purine and acetylcholine release from rat cerebral cortex: Evidence for a purinergic component in morphine's action. Pharmacol Biochem Behav  13: 421-427[Medline].
  • Phillis JW and Kostopoulos GK (1975) Adenosine as a putative transmitter in the cerebral cortex: Studies with potentiators and antagonists. Life Sci  17: 1085-1094[Medline].
  • Piazza PV and Le Moal M (1998) The role of stress in drug self-administration. Trends Pharmacol Sci  19: 67-74[Medline].
  • Pickworth WB (1995) Caffeine dependence. Lancet  345: 1066[Medline].
  • Pietinen P, Vartiainen E, Seppanen R, Aro A and Puska P (1996) Changes in diet in Finland from 1972 to 1992: Impact on coronary heart disease risk. Prev Med  25: 243-250[Medline].
  • Pinna A, Di Chiara G, Wardas J and Morelli M (1996) Blockade of A2A adenosine receptors positively modulates turning behaviour and c-fos expression induced by D1 agonists in dopamine-denervated rats. Eur J Neurosci  8: 1176-1181[Medline].
  • Pollack AE and Fink JS (1996) Synergistic interaction between an adenosine antagonist and a D1 dopamine agonist on rotational behavior and striatal c-Fos induction in 6-hydroxydopamine-lesioned rats. Brain Res  743: 124-130[Medline].
  • Pontieri FE, Tanda G and Di Chiara G (1995) Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. Proc Natl Acad Sci USA  92: 12304-12308[Abstract/Free Full Text].
  • Pontieri FE, Tanda G, Orzi F and Di Chiara G (1996) Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature  382: 255-257[Medline].
  • Popoli P, Ferré S, Pezzola A, Reggio R, DeCarolis AS and Fuxe K (1996a) Stimulation of adenosine A1 receptors prevents the EEG arousal due to dopamine D-1 receptor activation in rabbits. Eur J Pharmacol  305: 123-126[Medline].
  • Popoli P, Gimenez-Llort L, Pezzola A, Reggio R, Martinez E, Fuxe K and Ferré S (1996b) Adenosine A1 receptor blockade selectively potentiates the motor effects induced by dopamine D1 receptor stimulation in rodents. Neurosci Lett  218: 209-213[Medline].
  • Popoli P, Pézzola A and de Carolis AS (1994) Modulation of striatal adenosine A1 and A2 receptors induces rotational behaviour in response to dopaminergic stimulation in intact rats. Eur J Pharmacol  257: 21-25[Medline].
  • Popoli P, Sagratella S and Scotti de Carolis A (1987) An EEG and behavioural study on the excitatory properties of caffeine in rabbits. Arch Int Pharmacodyn Ther  290: 5-15[Medline].
  • Porkka-Heiskanen T, Strecker RE, Thakkar M, Bjorkum AA, Greene RW and McCarley RW (1997) Adenosine: A mediator of the sleep-inducing effects of prolonged wakefulness. Science  276: 1265-1268[Abstract/Free Full Text].
  • Porrino LJ (1993) Functional consequences of acute cocaine treatment depend on route of administration. Psychopharmacology  112: 343-351[Medline].
  • Porrino LJ, Domer FR, Crane AM and Sokoloff L (1988) Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats. Neuropsychopharmacology  1: 109-118[Medline].
  • Porrino LJ, Lucignani G, Dow-Edwards D and Sokoloff L (1984) Correlation of dose-dependent effects of acute amphetamine administration on behavior and local cerebral metabolism in rats. Brain Res  307: 311-320[Medline].
  • Premont J, Perez M, Blanc G, Tassin JP, Thierry AM, Herve D and Bockaert J (1979) Adenosine-sensitive adenylate cyclase in rat brain homogenates: Kinetic characteristics, specificity, topographical, subcellular and cellular distribution. Mol Pharmacol  16: 790-804[Abstract].
  • Proctor WR, Baker RC and Dunwiddie TV (1985) Differential CNS sensitivity to PIA and theophylline in long-sleep and short-sleep mice. Alcohol  2: 387-391[Medline].
  • Puccio EM, McPhillips JB, Barrett-Connor E and Ganiats TG (1990) Clustering of atherogenic behaviors in coffee drinkers. Am J Public Health  80: 1310-1313[Abstract].
  • Quinlan P, Lane J and Aspinall L (1997) Effects of hot tea, coffee and water ingestion on physiological responses and mood: The role of caffeine, water and beverage type. Psychopharmacology  134: 164-173[Medline].
  • Racotta IS, Leblanc J and Richard D (1994) The effect of caffeine on food intake in rats: Involvement of corticotropin-releasing factor and the sympatho-adrenal system. Pharmacol Biochem Behav  48: 887-892[Medline].
  • Radulovacki M (1985) Role of adenosine in sleep in rats. Rev Clin Basic Pharmacol  5: 327-339.
  • Rainnie DG, Grunze HC, McCarley RW and Greene RW (1994) Adenosine inhibition of mesopontine cholinergic neurons: Implications for EEG arousal. Science  263: 689-692[Abstract/Free Full Text].
  • Rang HP, Dale MM and Ritter JM (1995) Pharmacology 3rd ed. pp 1-855, Churchill Livingstone, Edinburgh.
  • Reid PG, Watt AH, Penny WJ, Newby AC, Smith AP and Routledge PA (1991) Plasma adenosine concentrations during adenosine-induced respiratory stimulation in man. Eur J Clin Pharmacol  40: 175-180[Medline].
  • Reppert SM, Weaver DR, Stehle JH and Rivkees SA (1991) Molecular cloning and characterization of a rat A1-adenosine receptor that is widely expressed in brain and spinal cord. Mol Endocrinol  5: 1037-1048[Abstract].
  • Revelle W, Humphreys MS, Simon L and Gilliland K (1980) The interactive effect of personality, time of day, and caffeine: A test of the arousal model. J Exp Psychol General  109: 1-31[Medline].
  • Richardson NJ, Rogers PJ and Elliman NA (1996) Conditioned flavour preferences reinforced by caffeine consumed after lunch. Physiol Behav  60: 257-263[Medline].
  • Richardson NJ, Rogers PJ, Elliman NA and O'Dell RJ (1995) Mood and performance effects of caffeine in relation to acute and chronic caffeine deprivation. Pharmacol Biochem Behav  52: 313-320[Medline].
  • Richardson PJ, Kase H and Jenner PG (1997) Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease. Trends Pharmacol Sci  18: 338-344[Medline].
  • Rihs M, Müller C and Baumann P (1996) Caffeine consumption in hospitalized psychiatric patients. Eur Arch Psychiatry Clin Neurosci  246: 83-92[Medline].
  • Ritchie JM (1975) The xanthines, in The Pharmacological Basis of Therapeutics (Goodman LS andGilman A eds) pp 367-376, MacMillan, New York.
  • Rivenes SM, Bakerman PR and Miller MB (1997) Intentional caffeine poisoning in an infant. Pediatrics  99: 736-738[Free Full Text].
  • Rizzo AA, Stamps LE and Fehr LA (1988) Effects of caffeine withdrawal on motor performance and heart rate changes. Int J Psychophysiol  6: 9-14[Medline].
  • Robertson D, Wade D, Workman R, Woosley RL and Oates JA (1981) Tolerance to the humoral and hemodynamic effects of caffeine in man. J Clin Invest  67: 1111-1117[Medline].
  • Robertson GS, Vincent SR and Fibiger HC (1992) D1 and D2 dopamine receptors differentially regulate c-fos expression in striatonigral and striatopallidal neurons. Neuroscience  49: 285-296[Medline].
  • Rogers PJ, Richardson NJ and Elliman NA (1995) Overnight caffeine abstinence and negative reinforcement of preference for caffeine-containing drinks. Psychopharmacology  120: 457-462[Medline].
  • Rose JE (1987) Cigarette smoking blocks caffeine-induced arousal. Alcohol Drug Res  7: 49-55[Medline].
  • Rossetti ZL, Melis F, Carboni S and Gessa GL (1992) Dramatic depletion of mesolimbic extracellular dopamine after withdrawal from morphine, alcohol or cocaine: A common neurochemical substrate for drug dependence. Ann NY Acad Sci  654: 513-516[Medline].
  • Rubinstein M, Phillips TJ, Bunzow JR, Falzone TL, Dziewczapolski G, Zhang G, Fang Y, Larson JL, McDougall JA, Chester JA, Saez C, Pugsley TA, Gershanik O, Low MJ and Grandy DK (1997) Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell  90: 991-1001[Medline].
  • Rudolphi KA, Keil M, Fastbom J and Fredholm BB (1989) Ischaemic damage in gerbil hippocampus is reduced following upregulation of adenosine (A1) receptors by caffeine treatment. Neurosci Lett  103: 275-280[Medline].
  • Rush CR, Higgins ST, Hughes JR, Bickel WK and Wiegner MS (1993) Acute behavioral and cardiac effects of alcohol and caffeine, alone and in combination, in humans. Behav Pharmacol  4: 562-572.
  • Rush CR, Sullivan JT and Griffiths RR (1995) Intravenous caffeine in stimulant drug abusers: Subjective reports and physiological effects. J Pharmacol Exp Ther  273: 351-358[Abstract/Free Full Text].
  • Sather WA, Tanabe T, Zhang JF, Mori Y, Adams ME and Tsien RW (1993) Distinctive biophysical and pharmacological properties of class A (BI) calcium channel alpha 1 subunits. Neuron  11: 291-303[Medline].
  • Satoh S, Matsumura H, Suzuki F and Hayaishi O (1996) Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats. Proc Natl Acad Sci USA  93: 5980-5984[Abstract/Free Full Text].
  • Schechter MD (1977) Caffeine potentiation of amphetamine: Implications for hyperkinesis therapy. Pharmacol Biochem Behav  6: 359-361[Medline].
  • Schechter MD (1980) Caffeine potentiation of apomorphine discrimination. Pharmacol Biochem Behav  13: 307-309[Medline].
  • Schenk S, Valadez A, Horger BA, Snow S and Wellman PJ (1994) Interactions between caffeine and cocaine in tests of self-administration. Behav Pharmacol  5: 153-158[Medline].
  • Schenk S, Worley CM, McNamara C and Valadez A (1996) Acute and repeated exposure to caffeine: Effects on reinstatement of extinguished cocaine-taking behavior in rats. Psychopharmacology  126: 17-23[Medline].
  • Schiffman SS, Gill JM and Diaz C (1985) Methyl xanthines enhance taste: Evidence for modulation of taste by adenosine receptor. Pharmacol Biochem Behav  22: 195-203[Medline].
  • Schiffmann SN, Jacobs O and Vanderhaeghen JJ (1991) Striatal restricted adenosine A2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: An in situ hybridization histochemistry study. J Neurochem  57: 1062-1067[Medline].
  • Schlingensiepen KH, Luno K and Brysch W (1991) High basal expression of the zif/268 immediate early gene in cortical layers IV and VI, in CA1 and in the corpus striatum---an in situ hybridization study. Neurosci Lett  122: 67-70[Medline].
  • Scholz KP and Miller RJ (1992) Inhibition of quantal transmitter release in the absence of calcium influx by a G protein-linked adenosine receptor at hippocampal synapses. Neuron  8: 1139-1150[Medline].
  • Schuh KJ and Griffiths RR (1997) Caffeine reinforcement---the role of withdrawal. Psychopharmacology  130: 320-326[Medline].
  • Schultz W (1992) Activity of dopamine neurons in the behaving primate. Semin Neurosci  4: 129-138.
  • Schultz W, Dayan P and Montague PR (1997) A neural substrate of prediction and reward. Science  275: 1593-1599[Abstract/Free Full Text].
  • Schwierin B, Borbely AA and Tobler I (1996) Effects of N6-cyclopentyladenosine and caffeine on sleep regulation in the rat. Eur J Pharmacol  300: 163-171[Medline].
  • Searle GF (1994) The effect of dietary caffeine manipulation on blood caffeine, sleep and disturbed behaviour. J Intellect Disabil Res  38: 383-391[Medline].
  • Self DW (1992) The role of dopamine receptors and inhibitory G proteins in stimulant and opioid reinforcement. PhD Thesis, Univ Calif, Irvine 1-231.
  • Self DW, Barnhart WJ, Lehman DA and Nestler EJ (1996) Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonists. Science  271: 1586-1589[Abstract].
  • Self DW, Genova LM, Hope BT, Barnhart WJ, Spencer JJ and Nestler EJ (1998) Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior. J Neurosci  18: 1848-1859[Abstract/Free Full Text].
  • Self DW and Nestler EJ (1995) Molecular mechanisms of drug reinforcement and addiction. Annu Rev Neurosci  18: 463-495[Medline].
  • Seutin V, Verbanck P, Massotte L and Dresse A (1991) Acute amphetamine-induced subsensitivity of A10 dopamine autoreceptors in vitro. Brain Res  558: 141-144[Medline].
  • Sheng M and Greenberg ME (1990) The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron  4: 477-485[Medline].
  • Shi D, Nikodijevic O, Jacobson KA and Daly JW (1993a) Chronic caffeine alters the density of adenosine, adrenergic, cholinergic, GABA, and serotonin receptors and calcium channels in mouse brain. Cell Mol Neurobiol  13: 247-261[Medline].
  • Shi D, Nikodijevic O, Jacobson KA and Daly JW (1994) Effects of chronic caffeine on adenosine, dopamine and acetylcholine systems in mice. Arch Int Pharmacodyn Ther  328: 261-287[Medline].
  • Shi J, Benowitz NL, Denaro CP and Sheiner LB (1993b) Pharmacokinetic-pharmacodynamic modeling of caffeine: Tolerance to pressor effects. Clin Pharmacol Ther  53: 6-14[Medline].
  • Shimada S, Kitayama S, Lin C-L, Patel A, Nanthakumar E, Gregor P, Kuhar M and Uhl G (1991) Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA. Science  254: 576-578[Abstract/Free Full Text].
  • Shively CA and Tarka SM, Jr (1984) Methylxanthine composition and consumption patterns of cocoa and chocolate products, in The Methylxanthine Beverages and Foods: Chemistry, Consumption, and Health Effects (Spiller GA ed) pp 149-178, Alan R. Liss, Inc., New York.
  • Silinsky EM (1984) On the mechanism by which adenosine receptor activation inhibits the release of acetylcholine from motor nerve endings. J Physiol (Lond)  346: 243-256[Abstract].
  • Silverman K, Evans SM, Strain EC and Griffiths RR (1992) Withdrawal syndrome after the double-blind cessation of caffeine consumption. N Engl J Med  327: 1109-1114[Abstract].
  • Silverman K, Mumford GK and Griffiths RR (1994) Enhancing caffeine reinforcement by behavioral requirements following drug ingestion. Psychopharmacology  114: 424-432[Medline].
  • Smellie FW, Davis CW, Daly JW and Wells JN (1979) Alkylxanthines: Inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity. Life Sci  24: 2475-2482[Medline].
  • Smith A, Thomas M, Perry K and Whitney H (1997) Caffeine and the common cold. J Psychopharmacol  11: 319-324[Medline].
  • Smits P, Temme L and Thien T (1993) The cardiovascular interaction between caffeine and nicotine in humans. Clin Pharmacol Ther  54: 194-204[Medline].
  • Snaprud P, Gerwins P, Caron MG, Libert F, Persson H, Fredholm BB and Fuxe K (1994) A2a/D2 receptor interactions are not observed in COS-7 cells transiently transfected with dopamine D2 and adenosine A2a receptor cDNA. Biochem Pharmacol  48: 2043-2047[Medline].
  • Snel J (1993) Coffee and caffeine: Sleep and wakefulness, in Coffee, Caffeine and Health (Garattini S ed) pp 255-290, Raven Press, New York.
  • Sollevi A, Hjemdahl P and Fredholm BB (1981) Endogenous adenosine inhibits lipolysis induced by nerve stimulation without inhibiting noradrenaline release in canine subcutaneous adipose tissue in vivo. Naunyn-Schmiedebergs Arch Pharmacol  316: 112-119[Medline].
  • Somani SM, Khanna NN and Bada HS (1980) Caffeine and theophylline: Serum/CSF correlation in premature infants. J Pediatr  96: 1091-1093[Medline].
  • Soroko S, Chang J and Barrett-Connor E (1996) Reasons for changing caffeinated coffee consumption: The Rancho Bernardo Study. J Am Coll Nutr  15: 97-101[Abstract].
  • Stein EA and Fuller SA (1992) Selective effects of cocaine on regional cerebral blood flow in the rat. J Pharmacol Exp Ther  262: 327-334[Abstract/Free Full Text].
  • Stern KN, Chait LD and Johanson CE (1989) Reinforcing and subjective effects of caffeine in normal human volunteers. Psychopharmacology  98: 81-88[Medline].
  • Stoner GR, Skirboll LR, Werkman S and Hommer DW (1988) Preferential effects of caffeine on limbic and cortical dopamine systems. Biol Psychiatry  23: 761-768[Medline].
  • Strain EC, Mumford GK, Silverman K and Griffiths RR (1994) Caffeine dependence syndrome: Evidence from case histories and experimental evaluations. JAMA  272: 1043-1048[Abstract].
  • Streufert S, Satish U, Pogash R, Gingrich D, Landis R, Roache J and Severs W (1997) Excess coffee consumption in simulated complex work settings: Detriment or facilitation of performance? J Appl Psychol  82: 774-782[Medline].
  • Suzuki F, Shimada J, Shiozaki S, Ichikawa S, Ishii A, Nakamura J, Nonaka H, Kobayashi H and Fuse E (1993) Adenosine A1 antagonists: 3. Structure-activity relationships on amelioration against scopolamine- or N6-((R)-phenylisopropyl)adenosine-induced cognitive disturbance. J Med Chem  36: 2508-2518[Medline].
  • Svenningsson P and Fredholm BB (1997) Caffeine mimics the effect of a dopamine D2/3 receptor agonist on the expression of immediate early genes in globus pallidus. Neuropharmacology  36: 1309-1317[Medline].
  • Svenningsson P, Georgieva J, Kontny E, Heilig M and Fredholm BB (1997a) Caffeine regulates the preprotachykinin A and neurotensin/neuromedin N genes via a c-fos dependent mechanism in rat striatum. Eur J Neurosci  9: 2135-2141[Medline].
  • Svenningsson P, Johansson B and Fredholm BB (1996) Caffeine-induced expression of c-fos mRNA and NGFI-A mRNA in caudate putamen and in nucleus accumbens are differentially affected by the N-methyl-D-aspartate receptor antagonist MK-801. Brain Res Mol Brain Res  35: 183-189[Medline].
  • Svenningsson P, Le Moine C, Kull B, Sunahara R, Bloch B and Fredholm BB (1997b) Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas. Neuroscience  80: 1171-1185[Medline].
  • Svenningsson P, Lindskog M, Rognoni F, Fredholm BB, Greengard P and Fisone G (1998a) Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons. Neuroscience  84: 223-228[Medline].
  • Svenningsson P, Nergårdh R and Fredholm BB (1998b) Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat. Neuropharmacology  37: 331-337[Medline].
  • Svenningsson P, Nomikos GG and Fredholm BB (1995a) Biphasic changes in locomotor behavior and in expression of mRNA for NGFI-A and NGFI-B in rat striatum following acute caffeine administration. J Neurosci  15: 7612-7624[Abstract].
  • Svenningsson P, Nomikos GG, Ongini E and Fredholm BB (1997c) Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens. Neuroscience  79: 753-764[Medline].
  • Svenningsson P, Ström A, Johansson B and Fredholm BB (1995b) Increased expression of c-jun, junB, AP-1, and preproenkephalin mRNA in rat striatum following a single injection of caffeine. J Neurosci  15: 3583-3593[Abstract].
  • Swan GE, Carmelli D and Cardon LR (1996) The consumption of tobacco, alcohol, and coffee in Caucasian male twins: A multivariate genetic analysis. J Subst Abuse  8: 19-31[Medline].
  • Swanson JA, Lee JW and Hopp JW (1994) Caffeine and nicotine: A review of their joint use and possible interactive effects in tobacco withdrawal. Addict Behav  19: 229-256[Medline].
  • Takahashi T and Momiyama A (1993) Different types of calcium channels mediate central synaptic transmission. Nature  366: 156-158[Medline].
  • Tanaka H, Nakazawa K, Arima M and Iwasaki S (1984) Caffeine and its dimethylxanthines and fetal cerebral development in rat. Brain Dev  6: 355-361[Medline].
  • Tanaka Y, Sakurai M, Goto M and Hayashi S (1990) Effect of xanthine derivatives on hippocampal long-term potentiation. Brain Res  522: 63-68[Medline].
  • Tanda G, Pontieri FE and Di Chiara G (1997) Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu-1 opioid receptor mechanism. Science  276: 2048-2050[Abstract/Free Full Text].
  • Temple JG, Dember WN, Warm JS, Jones KS and LaGrange CM (1997) The effects of caffeine on performance and stress in an abbreviated vigilance task.Proceedings of the Human Factors and Ergonomics Society 41st Annual Meeting, Albuquerque, NM, 1293-1297.
  • Thelle DS, Arnesen E and Forde OH (1983) The Tromso heart study: Does coffee raise serum cholesterol? N Engl J Med  308: 1454-1457[Abstract].
  • Thelle DS, Heyden S and Fodor JG (1987) Coffee and cholesterol in epidemiological and experimental studies. Atherosclerosis  67: 97-103[Medline].
  • Thompson SM, Haas HL and Gähwiler BH (1992) Comparison of the actions of adenosine at pre- and postsynaptic receptors in the rat hippocampus in vitro. J Physiol (Lond)  451: 347-363[Abstract].
  • Ticho SR and Radulovacki M (1991) Role of adenosine in sleep and temperature regulation in the preoptic area of rats. Pharmacol Biochem Behav  40: 33-40[Medline].
  • Tiffin P, Ashton H, Marsh R and Kamali F (1995) Pharmacokinetic and pharmacodynamic responses to caffeine in poor and normal sleepers. Psychopharmacology  121: 494-502[Medline].
  • Tremblay A, Masson E, Leduc S, Houde A and Depres J-P (1988) Caffeine reduces spontaneous energy intake in men but not in women. Nutr Res  8: 553-558.
  • Tuazon DB, Suzuki T, Misawa M and Watanabe S (1992) Methylxanthines (caffeine and theophylline) blocked methamphetamine-induced conditioned place preference in mice but enhanced that induced by cocaine. Ann NY Acad Sci  654: 531-533[Medline].
  • Tuomilehto J and Pietinen P (1991) Coffee and cardiovascular disease. Cardiovasc Risk Factors  1: 165-173.
  • Turgeon SM, Pollack AE, Schusheim L and Fink JS (1996) Effects of selective adenosine A1 and A2a agonists on amphetamine-induced locomotion and c-Fos in striatum and nucleus accumbens. Brain Res  707: 75-80[Medline].
  • Turmen T, Louridas TA and Aranda JV (1979) Relationship of plasma and CSF concentrations of caffeine in neonates with apnea. J Pediatr  95: 644-646[Medline].
  • Uhde TW, Boulenger JP, Jimerson DC and Post RM (1984) Caffeine: Relationship to human anxiety, plasma MHPG and cortisol. Psychopharmacol Bull  20: 426-430[Medline].
  • Urgert R and Katan MB (1997) The cholesterol-raising factor from coffee beans. Annu Rev Nutr  17: 305-324[Medline].
  • van der Stelt O and Snel J (1993) Effects of caffeine on human information processing: A cognitive-energetic approach, in Caffeine, Coffee and Health (Garattini S ed) pp 291-316, Raven Press, New York.
  • van Dusseldorp M, Smits P, Thien T and Katan MB (1989) Effect of decaffeinated versus regular coffee on blood pressure: A 12-week, double-blind trial. Hypertension  14: 563-569[Abstract].
  • Viani R (1993) The composition of coffee, in Caffeine, Coffee and Health (Garattini S ed) pp 17-41, Raven Press, New York.
  • Viani R (1996) Caffeine consumption, in Proceedings of the Caffeine Workshop Thai FDA and ILSI, Bangkok.
  • Virus RM, Baglajewski T and Radulovacki M (1984) Circadian variation of [3H]N6-(L-phenylisopropyl)adenosine binding in rat brain. Neurosci Lett  46: 219-222[Medline].
  • Vitiello MV and Woods SC (1977) Evidence for withdrawal from caffeine by rats. Pharmacol Biochem Behav  6: 553-555[Medline].
  • Von Lubitz DK, Paul IA, Bartus RT and Jacobson KA (1993a) Effects of chronic administration of adenosine A1 receptor agonist and antagonist on spatial learning and memory. Eur J Pharmacol  249: 271-280[Medline].
  • Von Lubitz DK, Paul IA, Carter M and Jacobson KA (1993b) Effects of N6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice. Eur J Pharmacol  249: 265-270[Medline].
  • Waldeck B (1975) Effect of caffeine on locomotor activity and central catecholamine mechanisms: A study with special reference to drug interaction. Acta Pharmacol Toxicol 36(Suppl IV):1-23.
  • Warburton DM (1995) Effects of caffeine on cognition and mood without caffeine abstinence. Psychopharmacology  119: 66-70[Medline].
  • Warburton DM and Thompson DH (1994) An evaluation of caffeine in terms of anxiety, depression and headache in the general population. Pharmacopsychoecologia  7: 55-62.
  • Ward N, Whitney C, Avery D and Dunner D (1991) The analgesic effects of caffeine in headache. Pain  44: 151-155[Medline].
  • Watson MA and Milbrandt J (1989) The NGFI-B gene, a transcriptionally inducible member of the steroid receptor gene superfamily: Genomic structure and expression in rat brain after seizure induction. Mol Cell Biol  9: 4213-4219[Abstract/Free Full Text].
  • Watson MA and Milbrandt J (1990) Expression of the nerve growth factor-regulated NGFI-A and NGFI-B genes in the developing rat. Development  110: 173-183[Abstract].
  • Weber JG, Ereth MH and Danielson DR (1993) Perioperative ingestion of caffeine and postoperative headache. Mayo Clinic Proc  68: 842-845[Medline].
  • Weber JG, Klindworth JT, Arnold JJ, Danielson DR and Ereth MH (1997) Prophylactic intravenous administration of caffeine and recovery after ambulatory surgical procedures. Mayo Clinic Proc  72: 621-626[Medline].
  • Weidner G and Istvan J (1985) Dietary sources of caffeine. N Engl J Med  313: 1421[Medline].
  • White FJ (1996) Synaptic regulation of mesocorticolimbic dopamine neurons. Annu Rev Neurosci  19: 405-436[Medline].
  • White JM (1994) Behavioral effects of caffeine coadministered with nicotine, benzodiazepines and alcohol. Pharmacopsychoecologia  7: 119-126.
  • Wikler A (1973) Dynamics of drug dependence: Implications of a conditioning theory for research and treatment. Arch Gen Psychiatry  28: 611-616[Medline].
  • Willett WC, Stampfer MJ, Manson JE, Colditz GA, Rosner BA, Speizer FE and Hennekens CH (1996) Coffee consumption and coronary heart disease in women: A ten-year follow-up. JAMA  275: 458-462[Abstract].
  • Winter JC (1981) Caffeine-induced stimulus control. Pharmacol Biochem Behav  15: 157-159[Medline].
  • Wise RA (1996) Addictive drugs and brain stimulation reward. Annu Rev Neurosci  19: 319-340[Medline].
  • Wise RA and Bozarth MA (1987) A psychomotor stimulant theory of addiction. Psychol Rev  94: 469-492[Medline].
  • Wise R (1988) The neurobiology of craving: Implications for the understanding and treatment of addiction. J Abnorm Psychol  97: 118-132[Medline].
  • Wolf ME, White FJ and Hu XT (1994) MK-801 prevents alterations in the mesoaccumbens dopamine system associated with behavioral sensitization to amphetamine. J Neurosci  14: 1735-1745[Abstract].
  • Worley CM, Valadez A and Schenk S (1994) Reinstatement of extinguished cocaine-taking behavior by cocaine and caffeine. Pharmacol Biochem Behav  48: 217-221[Medline].
  • Worley PF, Christy BA, Nakabeppu Y, Bhat RV, Cole AJ and Baraban JM (1991) Constitutive expression of zif268 in neocortex is regulated by synaptic activity. Proc Natl Acad Sci USA  88: 5106-5110[Abstract/Free Full Text].
  • World Health Organization (1957) Expert committee on addiction-producing drugs, Seventh report, in Technical Report Series pp 1-15, WHO, Geneva.
  • World Health Organization (1992) The ICD-10 Classification of Mental and Behavioural Disorders WHO, Geneva.
  • Wright KP, Jr, Badia P, Myers BL and Plenzler SC (1997) Combination of bright light and caffeine as a countermeasure for impaired alertness and performance during extended sleep deprivation. J Sleep Res  6: 26-35[Medline].
  • Wu LG and Saggau P (1994) Presynaptic calcium is increased during normal synaptic transmission and paired-pulse facilitation, but not in long-term potentiation in area CA1 of hippocampus. J Neurosci  14: 645-654[Abstract].
  • Xu M, Hu X-T, Cooper DC, Moratalla R, Graybiel AM, White FJ and Tonegawa S (1994) Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice. Cell  79: 945-955[Medline].
  • Yanik G, Glaum S and Radulovacki M (1987) The dose-response effects of caffeine on sleep in rats. Brain Res  403: 177-180[Medline].
  • Yawo H and Chuhma N (1993) Preferential inhibition of omega-conotoxin-sensitive presynaptic Ca2+ channels by adenosine autoreceptors. Nature  365: 256-257[Medline].
  • Zarrindast MR and Moghadamnia AA (1997) Adenosine receptor agents and conditioned place preference. Gen Pharmacol  29: 285-289[Medline].
  • Zetterström T, Vernet L, Ungerstedt U, Tossman U, Jonzon B and Fredholm BB (1982) Purine levels in the intact rat brain: Studies with an implanted perfused hollow fibre. Neurosci Lett  29: 111-115[Medline].
  • Zwyghuizen-Doorenbos A, Roehrs TA, Lipschutz L, Timms V and Roth T (1990) Effects of caffeine on alertness. Psychopharmacology  100: 36-39[Medline].

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