SM carried out microscopy and quantification studies. JE isolated and purified rat liver nuclei and contributed to writing of the paper. RVM carried out microinjection and analysis of these data. ED contributed LA dsRed cells. BDW and UN contributed to design of experiments and writing of the paper. SLS proposed the hypothesis, carried out the in vitro analysis of CD-BODIPY and conceived and designed experiments. SM and SLS wrote the paper. All authors read and approved the final manuscript.